Detailed information NTG0037611

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: HMPREF0837_RS07230
• Genome accession: NC_014251
• Coordinates: 1392540..1393493 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae TCH8431/19A
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1387540..1398493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0837_RS12425	-	1388020..1388115 (-)	96	Protein_1375	IS630 family transposase	-
HMPREF0837_RS07210 (HMPREF0837_11507)	-	1388528..1388869 (+)	342	Protein_1376	transposase	-
HMPREF0837_RS07215 (HMPREF0837_11508)	prsA	1388986..1389927 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
HMPREF0837_RS07220 (HMPREF0837_11509)	-	1389995..1390708 (-)	714	WP_000230400.1	O-methyltransferase	-
HMPREF0837_RS07225 (HMPREF0837_11510)	pepF	1390710..1392521 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
HMPREF0837_RS07230 (HMPREF0837_11511)	coiA	1392540..1393493 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
HMPREF0837_RS07235 (HMPREF0837_11512)	tehB	1393566..1394426 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
HMPREF0837_RS07240 (HMPREF0837_11513)	smpB	1394442..1394909 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
HMPREF0837_RS07245 (HMPREF0837_11514)	rnr	1394872..1397226 (-)	2355	WP_000654886.1	ribonuclease R	-
HMPREF0837_RS07250 (HMPREF0837_11515)	secG	1397328..1397561 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
HMPREF0837_RS07255	rpmG	1397601..1397750 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=37611 HMPREF0837_RS07230 WP_000495909.1 1392540..1393493(-) (coiA) [Streptococcus pneumoniae TCH8431/19A]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=37611 HMPREF0837_RS07230 WP_000495909.1 1392540..1393493(-) (coiA) [Streptococcus pneumoniae TCH8431/19A]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435