Detailed information    

experimental Experimentally validated

Overview

Name   ctsW   Type   Unclear
Locus tag   CJJ81176_RS04995 Genome accession   NC_008787
Coordinates   966931..967506 (-) Length   191 a.a.
NCBI ID   WP_002853564.1    Uniprot ID   A0AB36G5T1
Organism   Campylobacter jejuni subsp. jejuni 81-176     
Function   require for natural transformation   
Unclear

Function

Mutant C23 and ctsW::solo take up DNA at levels approaching that of the wild type. This suggests that the transformation defect in these two mutants lies in a later stage of transformation, such as transport to the cytoplasm or recombination with the chromosome.


Genomic Context

Location: 961931..972506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJJ81176_RS04975 (CJJ81176_1043) flgR 961935..963236 (-) 1302 WP_002869127.1 fla regulon two-component system response regulator -
  CJJ81176_RS04980 (CJJ81176_1044) flgQ 963293..963742 (-) 450 WP_002869126.1 flagellar assembly protein FlgQ -
  CJJ81176_RS04985 (CJJ81176_1045) flgP 963718..964233 (-) 516 WP_002852972.1 flagellar assembly lipoprotein FlgP -
  CJJ81176_RS04990 (CJJ81176_1046) gyrA 964302..966890 (-) 2589 WP_002869125.1 DNA topoisomerase (ATP-hydrolyzing) subunit A -
  CJJ81176_RS04995 (CJJ81176_1047) ctsW 966931..967506 (-) 576 WP_002853564.1 ComF family protein Unclear
  CJJ81176_RS05000 (CJJ81176_1048) mapA 967503..968147 (-) 645 WP_002869124.1 outer membrane lipoprotein MapA -
  CJJ81176_RS05005 (CJJ81176_1049) lepA 968224..970020 (-) 1797 WP_002837927.1 translation elongation factor 4 -
  CJJ81176_RS05010 (CJJ81176_1050) cmeD 970146..971420 (+) 1275 WP_002855787.1 multidrug efflux RND transporter outer membrane subunit CmeD -
  CJJ81176_RS05015 (CJJ81176_1051) cmeE 971417..972157 (+) 741 WP_002855808.1 multidrug efflux RND transporter periplasmic adaptor subunit CmeE -

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22394.41 Da        Isoelectric Point: 9.5211

>NTDB_id=1233 CJJ81176_RS04995 WP_002853564.1 966931..967506(-) (ctsW) [Campylobacter jejuni subsp. jejuni 81-176]
MRCINCGAFALLCFCELCELELSEFSLNVRKLDNNFKVYSFYKYHEIQHLLHSKHYFYGYFVYKMLAKLSFAKFKDFFDP
RMTINVIALDDKVEDMLYSHSAILARYLKTKFVKPVFNVLKAQNHIKYSGKSLEFRQKHKRNYKLLKTIHEPVILVDDIV
TTGSSLLEAKKVLEENKISVLFALVLADAKV

Nucleotide


Download         Length: 576 bp        

>NTDB_id=1233 CJJ81176_RS04995 WP_002853564.1 966931..967506(-) (ctsW) [Campylobacter jejuni subsp. jejuni 81-176]
TTGAGGTGTATAAATTGCGGAGCTTTTGCTCTGCTCTGCTTTTGTGAATTATGCGAGCTAGAGCTTTCTGAATTTTCCTT
AAATGTAAGAAAGCTTGATAATAATTTCAAAGTCTATTCTTTTTATAAATACCATGAAATACAACACTTGCTTCACTCTA
AACATTATTTTTATGGTTATTTTGTTTATAAAATGCTTGCTAAATTAAGTTTTGCAAAATTTAAAGATTTTTTTGATCCT
AGAATGACAATTAATGTTATAGCTTTAGATGATAAGGTTGAAGATATGCTTTATTCGCATTCTGCTATTTTAGCTAGATA
TCTTAAAACAAAATTTGTAAAACCTGTTTTTAATGTTTTAAAAGCACAAAATCATATTAAATATTCTGGAAAAAGTTTAG
AATTTCGTCAAAAACATAAAAGAAATTACAAACTCTTAAAAACCATTCACGAACCTGTAATTTTAGTAGATGATATTGTA
ACGACTGGTTCTAGCCTTTTGGAAGCTAAAAAAGTTTTAGAAGAAAATAAAATTTCTGTACTTTTTGCTCTTGTTTTAGC
TGATGCAAAAGTTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC Helicobacter pylori 26695

36.979

100

0.372

Multiple sequence alignment    



References

[1] Rebecca S Wiesner et al. (2003) Natural transformation of Campylobacter jejuni requires components of a type II secretion system. Journal of Bacteriology 185(18):5408-18. [PMID: 12949093]