Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HAP53_RS02170 Genome accession   NZ_CP049979
Coordinates   471942..472532 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain IBS28     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 466942..477532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAP53_RS02145 (HAP53_02145) emrD 467424..468608 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  HAP53_RS23680 ysdE 468690..468764 (+) 75 WP_211180519.1 protein YsdE -
  HAP53_RS02150 (HAP53_02150) tisB 469027..469116 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  HAP53_RS02155 (HAP53_02155) ivbL 469681..469779 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  HAP53_RS02160 (HAP53_02160) ilvB 469885..471573 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  HAP53_RS02165 (HAP53_02165) ilvN 471577..471867 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  HAP53_RS02170 (HAP53_02170) letA 471942..472532 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  HAP53_RS02175 (HAP53_02175) uhpB 472532..474034 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  HAP53_RS02180 (HAP53_02180) uhpC 474044..475363 (+) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  HAP53_RS02185 (HAP53_02185) uhpT 475501..476892 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=375995 HAP53_RS02170 WP_000633668.1 471942..472532(+) (letA) [Escherichia coli strain IBS28]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=375995 HAP53_RS02170 WP_000633668.1 471942..472532(+) (letA) [Escherichia coli strain IBS28]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment