Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FP508_RS05225 Genome accession   NZ_CP041998
Coordinates   1012856..1014169 (-) Length   437 a.a.
NCBI ID   WP_185159754.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS7     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1007856..1019169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP508_RS05205 (FP508_05365) - 1009336..1010109 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  FP508_RS05210 (FP508_05370) - 1010099..1010785 (-) 687 WP_000280308.1 SatD family protein -
  FP508_RS05215 (FP508_05375) ffh 1010852..1012417 (-) 1566 WP_000863589.1 signal recognition particle protein -
  FP508_RS05220 (FP508_05380) - 1012435..1012767 (-) 333 WP_000402075.1 putative DNA-binding protein -
  FP508_RS05225 (FP508_05385) ciaH 1012856..1014169 (-) 1314 WP_185159754.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FP508_RS05230 (FP508_05390) ciaR 1014153..1014833 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  FP508_RS05235 (FP508_05395) - 1014995..1017544 (-) 2550 WP_000859382.1 M1 family metallopeptidase -
  FP508_RS05240 (FP508_05400) phoU 1017690..1018343 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  FP508_RS05245 (FP508_05405) pstB 1018377..1019135 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49690.17 Da        Isoelectric Point: 9.4961

>NTDB_id=375318 FP508_RS05225 WP_185159754.1 1012856..1014169(-) (ciaH) [Streptococcus agalactiae strain GBS7]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRIPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=375318 FP508_RS05225 WP_185159754.1 1012856..1014169(-) (ciaH) [Streptococcus agalactiae strain GBS7]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTATTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae D39

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae R6

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.905

96.11

0.499

Multiple sequence alignment