Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   G7052_RS00815 Genome accession   NZ_CP049799
Coordinates   161368..162150 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain 1040     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 156368..167150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7052_RS00790 (G7052_00790) gatB 156449..157888 (-) 1440 WP_063632095.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  G7052_RS00795 (G7052_00795) gatA 157888..159354 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  G7052_RS00800 (G7052_00800) gatC 159354..159656 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  G7052_RS00805 (G7052_00805) - 159888..160190 (-) 303 Protein_147 putative PEP-binding protein -
  G7052_RS00810 (G7052_00810) - 160667..161221 (-) 555 WP_002992568.1 isochorismatase family cysteine hydrolase -
  G7052_RS00815 (G7052_00815) codY 161368..162150 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  G7052_RS00820 (G7052_00820) - 162368..163582 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  G7052_RS00825 (G7052_00825) - 163813..164265 (+) 453 WP_002983265.1 universal stress protein -
  G7052_RS00830 (G7052_00830) - 164388..165776 (-) 1389 WP_038434237.1 Cof-type HAD-IIB family hydrolase -
  G7052_RS00835 (G7052_00835) - 165848..166813 (+) 966 WP_023078713.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=375231 G7052_RS00815 WP_002983278.1 161368..162150(-) (codY) [Streptococcus pyogenes strain 1040]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=375231 G7052_RS00815 WP_002983278.1 161368..162150(-) (codY) [Streptococcus pyogenes strain 1040]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment