Detailed information NTG0374847

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: FOZ66_RS25940
• Genome accession: NZ_CP041945
• Coordinates: 5516156..5517493 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain ST773
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5511156..5522493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOZ66_RS25915 (FOZ66_26630)	pgeF	5511299..5512027 (-)	729	WP_015503650.1	peptidoglycan editing factor PgeF	-
FOZ66_RS25920 (FOZ66_26635)	rluD	5512024..5512986 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
FOZ66_RS25925 (FOZ66_26640)	-	5513132..5514157 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
FOZ66_RS25930 (FOZ66_26645)	-	5514314..5514559 (+)	246	WP_003102591.1	PP0621 family protein	-
FOZ66_RS25935 (FOZ66_26650)	pilS	5514549..5516141 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
FOZ66_RS25940 (FOZ66_26655)	pilR	5516156..5517493 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
FOZ66_RS25945 (FOZ66_26660)	thiO	5517539..5518633 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
FOZ66_RS25950 (FOZ66_26665)	-	5518773..5519273 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
FOZ66_RS25955 (FOZ66_26670)	-	5519396..5519884 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
FOZ66_RS25960 (FOZ66_26675)	pilV	5519894..5520418 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
FOZ66_RS25965 (FOZ66_26680)	-	5520427..5521242 (+)	816	WP_016254061.1	PilW family protein	-
FOZ66_RS25970 (FOZ66_26685)	-	5521239..5521844 (+)	606	WP_003116263.1	pilus assembly PilX family protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=374847 FOZ66_RS25940 WP_003094694.1 5516156..5517493(+) (pilR) [Pseudomonas aeruginosa strain ST773]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=374847 FOZ66_RS25940 WP_003094694.1 5516156..5517493(+) (pilR) [Pseudomonas aeruginosa strain ST773]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTACGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384