NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	G8B41_RS08585	Genome accession	NZ_CP049691
Coordinates	1752593..1753189 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain ABC199
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1747593..1758189

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G8B41_RS08550 (G8B41_08625)	-	1747653..1747958 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
G8B41_RS08555 (G8B41_08630)	ruvX	1747970..1748389 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
G8B41_RS08560 (G8B41_08635)	-	1748386..1748655 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
G8B41_RS08565 (G8B41_08640)	spx	1748769..1749167 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
G8B41_RS08570 (G8B41_08645)	recA	1749458..1750594 (-)	1137	WP_002992179.1	recombinase RecA	-
G8B41_RS08575 (G8B41_08650)	cinA	1750683..1751954 (-)	1272	WP_002992182.1	competence/damage-inducible protein A	Machinery gene
G8B41_RS08580 (G8B41_08655)	-	1752023..1752583 (-)	561	WP_002992183.1	DNA-3-methyladenine glycosylase I	-
G8B41_RS08585 (G8B41_08660)	ruvA	1752593..1753189 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
G8B41_RS08590 (G8B41_08665)	-	1753191..1754411 (-)	1221	WP_011529098.1	MFS transporter	-
G8B41_RS08595 (G8B41_08670)	hexB	1754422..1756404 (-)	1983	WP_021299132.1	DNA mismatch repair endonuclease MutL	Machinery gene
G8B41_RS08600 (G8B41_08675)	-	1756499..1757644 (-)	1146	WP_021299091.1	site-specific integrase	-
G8B41_RS08605 (G8B41_08680)	-	1757847..1757990 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=374632 G8B41_RS08585 WP_002992186.1 1752593..1753189(-) (ruvA) [Streptococcus pyogenes strain ABC199]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=374632 G8B41_RS08585 WP_002992186.1 1752593..1753189(-) (ruvA) [Streptococcus pyogenes strain ABC199]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG0374632