Detailed information NTG0374192

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: FOY97_RS27190
• Genome accession: NZ_CP041774
• Coordinates: 5621686..5623023 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 60503
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5616686..5628023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOY97_RS27165 (FOY97_27165)	pgeF	5616829..5617557 (-)	729	WP_015503650.1	peptidoglycan editing factor PgeF	-
FOY97_RS27170 (FOY97_27170)	rluD	5617554..5618516 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
FOY97_RS27175 (FOY97_27175)	-	5618662..5619687 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
FOY97_RS27180 (FOY97_27180)	-	5619844..5620089 (+)	246	WP_003102591.1	PP0621 family protein	-
FOY97_RS27185 (FOY97_27185)	pilS	5620079..5621671 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
FOY97_RS27190 (FOY97_27190)	pilR	5621686..5623023 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
FOY97_RS27195 (FOY97_27195)	thiO	5623069..5624163 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
FOY97_RS27200 (FOY97_27200)	-	5624303..5624803 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
FOY97_RS27205 (FOY97_27205)	-	5624926..5625414 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
FOY97_RS27210 (FOY97_27210)	pilV	5625424..5625948 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
FOY97_RS27215 (FOY97_27215)	-	5625957..5626772 (+)	816	WP_016254061.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
FOY97_RS27220 (FOY97_27220)	-	5626769..5627374 (+)	606	WP_003116263.1	pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=374192 FOY97_RS27190 WP_003094694.1 5621686..5623023(+) (pilR) [Pseudomonas aeruginosa strain 60503]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=374192 FOY97_RS27190 WP_003094694.1 5621686..5623023(+) (pilR) [Pseudomonas aeruginosa strain 60503]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTACGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384