Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FO459_RS01400 Genome accession   NZ_CP041727
Coordinates   271749..272378 (+) Length   209 a.a.
NCBI ID   WP_002461333.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain SL122     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 266749..277378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FO459_RS01375 (FO459_01375) - 267501..268481 (-) 981 WP_002477959.1 FUSC family protein -
  FO459_RS01380 (FO459_01380) map 268726..269481 (+) 756 WP_002461338.1 type I methionyl aminopeptidase -
  FO459_RS01385 (FO459_01385) - 269607..269993 (+) 387 WP_002477960.1 hypothetical protein -
  FO459_RS01390 (FO459_01390) liaF 270018..270719 (+) 702 WP_002461335.1 cell wall-active antibiotics response protein LiaF -
  FO459_RS01395 (FO459_01395) vraS 270716..271759 (+) 1044 WP_002461334.1 sensor histidine kinase Regulator
  FO459_RS01400 (FO459_01400) vraR 271749..272378 (+) 630 WP_002461333.1 two-component system response regulator VraR Regulator
  FO459_RS01405 (FO459_01405) - 272551..273780 (-) 1230 WP_002461332.1 YihY/virulence factor BrkB family protein -
  FO459_RS01410 (FO459_01410) - 273983..274267 (-) 285 WP_002461330.1 YtxH domain-containing protein -
  FO459_RS01415 (FO459_01415) - 274274..274738 (-) 465 WP_002477961.1 low molecular weight protein-tyrosine-phosphatase -
  FO459_RS01420 (FO459_01420) - 274902..275087 (+) 186 WP_002492715.1 DUF1128 domain-containing protein -
  FO459_RS01425 (FO459_01425) - 275100..276338 (+) 1239 WP_002477963.1 aminopeptidase -
  FO459_RS01430 (FO459_01430) - 276372..276899 (+) 528 WP_070873962.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23658.47 Da        Isoelectric Point: 5.3841

>NTDB_id=373542 FO459_RS01400 WP_002461333.1 271749..272378(+) (vraR) [Staphylococcus lugdunensis strain SL122]
MTIKVLFVDDHEMVRIGISSYLSTQPDLEVVGEGASGKEAIAKAQELKPDLILMDLLMEDMDGVEATTQIKKEMPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=373542 FO459_RS01400 WP_002461333.1 271749..272378(+) (vraR) [Staphylococcus lugdunensis strain SL122]
ATGACAATTAAAGTACTATTTGTAGATGACCATGAAATGGTAAGAATAGGAATTTCTAGTTATTTATCTACTCAGCCAGA
CCTTGAAGTTGTAGGTGAAGGTGCTTCTGGTAAAGAGGCAATAGCTAAAGCACAAGAATTAAAGCCAGATTTAATCTTGA
TGGATTTATTAATGGAAGACATGGATGGCGTCGAAGCGACAACGCAAATCAAGAAAGAGATGCCTCATATTAAAGTTGTA
ATGCTGACTAGCTTTATTGAGGATAAAGAAGTATATAGAGCGTTAGACGCTGGTGTTGACAGCTATATTTTAAAAACAAC
AAGCGCTAAAGATATCGCTGAAGCAGTGCGCAAAACATATCATGGAGAATCTGTATTTGAACCGGAAGTTCTGGTAAAAA
TGCGAAATAGAATGAAAAAACGTGCAGAGCTATATGAAATGTTAACAGAACGAGAAATGGAAATTTTACTGTTAATTGCT
AAAGGATATTCTAATCAAGAAATCGCAAGCGCATCACACATTACTATTAAAACAGTTAAAACACATGTGAGTAATATTTT
AAGCAAATTAGAAGTACAAGACCGTACACAAGCAGTAATCTATGCATTTCAGCACAATCTTATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment