Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   G6Z93_RS03565 Genome accession   NZ_CP049204
Coordinates   744835..745494 (-) Length   219 a.a.
NCBI ID   WP_021574775.1    Uniprot ID   -
Organism   Escherichia coli strain PapM-32-1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 739835..750494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6Z93_RS03540 (G6Z93_03540) - 740577..741524 (+) 948 WP_001305988.1 iron-siderophore ABC transporter substrate-binding protein -
  G6Z93_RS03545 (G6Z93_03545) - 741521..742408 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  G6Z93_RS03550 (G6Z93_03550) ygiN 742453..742767 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  G6Z93_RS03555 (G6Z93_03555) mdaB 742798..743379 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  G6Z93_RS03560 (G6Z93_03560) qseC 743489..744838 (-) 1350 WP_121865492.1 quorum sensing histidine kinase QseC -
  G6Z93_RS03565 (G6Z93_03565) ciaR 744835..745494 (-) 660 WP_021574775.1 quorum sensing response regulator transcription factor QseB Regulator
  G6Z93_RS03570 (G6Z93_03570) ygiW 745646..746038 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  G6Z93_RS03575 (G6Z93_03575) ygiV 746091..746573 (+) 483 WP_094281203.1 GyrI-like domain-containing protein -
  G6Z93_RS03580 (G6Z93_03580) ygiS 746682..748289 (+) 1608 WP_094281201.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24704.67 Da        Isoelectric Point: 6.3527

>NTDB_id=373243 G6Z93_RS03565 WP_021574775.1 744835..745494(-) (ciaR) [Escherichia coli strain PapM-32-1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLILKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=373243 G6Z93_RS03565 WP_021574775.1 744835..745494(-) (ciaR) [Escherichia coli strain PapM-32-1]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAATACTGAAACCAAAAGAATTTGCTCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365