Detailed information NTG0372933

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: FOG18_RS05505
• Genome accession: NZ_CP041668
• Coordinates: 1213789..1216524 (-)
• Length: 911 a.a.
• NCBI ID: WP_143866826.1
• Uniprot ID: -
• Organism: Legionella israelensis strain L18-01051
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1208789..1221524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOG18_RS05480 (FOG18_05480)	-	1209768..1210199 (-)	432	WP_143866818.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
FOG18_RS05485 (FOG18_05485)	-	1210192..1210512 (-)	321	WP_342353809.1	BolA family protein	-
FOG18_RS05490 (FOG18_05490)	-	1210700..1211152 (+)	453	WP_143866820.1	hypothetical protein	-
FOG18_RS05495 (FOG18_05495)	pilA2	1211393..1211812 (+)	420	WP_185967349.1	pilin	Machinery gene
FOG18_RS05500 (FOG18_05500)	-	1212508..1213758 (-)	1251	WP_143866824.1	6-phosphofructokinase	-
FOG18_RS05505 (FOG18_05505)	letS	1213789..1216524 (-)	2736	WP_143866826.1	two-component system sensor histidine kinase LetS	Regulator
FOG18_RS13990	-	1216599..1216829 (+)	231	WP_058502248.1	hypothetical protein	-
FOG18_RS05510 (FOG18_05510)	gltX	1216801..1218213 (+)	1413	WP_143866828.1	glutamate--tRNA ligase	-
FOG18_RS05515 (FOG18_05515)	-	1218274..1218762 (-)	489	WP_143866830.1	YchJ family metal-binding protein	-
FOG18_RS05520 (FOG18_05520)	-	1218886..1219596 (+)	711	WP_143866832.1	glutathione S-transferase C-terminal domain-containing protein	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 103467.73 Da
• Isoelectric Point: 7.7284

>NTDB_id=372933 FOG18_RS05505 WP_143866826.1 1213789..1216524(-) (letS) [Legionella israelensis strain L18-01051]
MKSLGIKYQLRITTLIPVLLVALLFALFYNGQFSKDLKQHMSRLGEAYIRQLMPAAQYALQQDNHRTLQGLINASTINQE
VKAVAFYDANGRLLAYRGGKHSLKKPFTPPAFTGDFIESKQLNSTTINFFAPITIPKYNLYSTDILRPSTQNFILQPDDI
LGWLSINIDTQSMLIKRYQMLIVTIFITLFGLLIGLATHYFLSKRIYMPISRLRRSMKQILRNEFETEIRVSSAGELGVI
EEGCAHLQKQYLDTIRDLNHHIEVATADLQQSLELLEEKNIELSMEKKKSEEKNRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKTSAQDLLQIINDILDYSKMDAGKLHLDCIPLDIRACIDEVLVLSAPNAHKKGIDLIPITSL
EVPRTVLGDPLRIKQIISNLVNNAIKFTDKGYVLIRTEVEQEMANDYLLRISVSDTGIGISKEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLAEEMKGRISLSSELHKGSTFSVHIRVEKLSSYEVEKNQNYRFAHLKVLCFDENRLQLESITNGL
GHWGIQCTTVNAFDKLAKALEHNKNCDFAFINVKQGYEAQIADLLKAHPNKTYILVSKWPIADVKSFGAQVFLYQPISIQ
KLHDIIESLMHQPSVPPSLVPQEVENLREQLRFSHPDILIAEDNPVNRMLLNSLLGENANMESVSDGEQAVVICNEKRFQ
VILLDLQMPKLNGLEAAKKIRHESLLNRHTPILLLSASSTDINRDKLKNAGIDHCLHKPVEEKQLISHLLRLMDKAQHAA
IDWSLCVQKLSGNQKLAEDFLARFVEELKKDRLELIQLMRDKNIRGLASAAHKLHGACSFCGVPMLQKKVREFEIMTQQV
KNSEDLRSLFAELVQRIDAVIDEYENYYSEP

Nucleotide

• Length: 2736 bp

>NTDB_id=372933 FOG18_RS05505 WP_143866826.1 1213789..1216524(-) (letS) [Legionella israelensis strain L18-01051]
TTGAAAAGCCTTGGTATTAAATACCAGCTCAGGATTACAACACTTATTCCTGTGCTTCTCGTCGCTTTATTGTTTGCCTT
ATTTTATAACGGTCAATTCAGCAAAGATTTAAAACAACACATGTCGCGTCTCGGCGAAGCTTACATTCGCCAATTAATGC
CAGCTGCTCAGTATGCCTTACAGCAGGATAACCATCGGACTCTGCAAGGGCTCATTAACGCTTCTACCATCAATCAGGAA
GTGAAAGCCGTTGCTTTCTACGATGCCAATGGACGGCTGCTCGCTTATCGCGGAGGAAAACATTCTCTGAAAAAACCCTT
TACTCCTCCAGCCTTTACCGGTGATTTTATAGAAAGCAAGCAACTGAATTCTACCACCATTAATTTTTTCGCCCCCATCA
CTATCCCAAAATATAACTTATATTCCACGGATATACTGAGACCTTCAACCCAGAATTTTATTTTACAGCCAGATGATATT
TTGGGATGGCTGTCTATCAATATTGATACCCAATCCATGTTGATCAAGCGCTATCAAATGTTGATTGTTACGATTTTTAT
TACGCTGTTTGGATTACTGATTGGCTTGGCCACGCATTATTTTTTGTCAAAACGCATTTATATGCCTATCAGCCGATTAC
GCAGGAGCATGAAACAGATTTTAAGGAATGAATTTGAGACAGAAATTCGGGTTTCAAGCGCAGGGGAGCTGGGTGTTATT
GAGGAGGGCTGTGCCCATTTGCAGAAACAGTATCTCGACACCATACGTGATCTGAATCATCATATTGAAGTGGCCACGGC
TGACCTACAGCAAAGCCTTGAATTGCTGGAAGAAAAAAACATTGAATTATCGATGGAGAAGAAAAAATCAGAAGAAAAGA
ACCGGCAAAAATCAGAATTCATTGCCAACATGAGTCATGAAATCCGCACCCCTATGAATGGGGTGATTGGTTTTACTAAC
GTATTGCTGGAAAGTAAACTGGATCCCTTACAGCTCGATTATGTTAAAACGATCAAAACTTCTGCTCAGGATCTATTACA
AATCATCAACGACATTCTTGATTATTCAAAAATGGATGCCGGTAAACTCCATCTCGACTGTATACCTCTTGACATACGGG
CCTGCATTGATGAAGTTCTTGTTCTTTCTGCTCCCAATGCTCACAAAAAAGGCATTGACTTGATTCCAATTACCTCTCTC
GAGGTTCCAAGAACGGTTCTCGGTGATCCATTACGCATTAAACAAATCATATCCAATCTGGTGAACAATGCCATAAAATT
CACCGATAAAGGATACGTTCTTATCCGAACCGAGGTTGAGCAGGAGATGGCAAATGATTACCTGCTTCGCATCTCTGTAT
CCGATACCGGCATCGGGATTTCAAAAGAGGATCAGAGTAAATTATTTACAGCCTTCAATCAGGCCGATACCAGCATTACC
CGTCGCTACGGCGGCTCCGGCCTTGGCCTTGTCATTTGCAAGAAACTGGCTGAAGAAATGAAAGGACGCATCAGTCTGAG
TAGTGAATTACATAAAGGCTCAACCTTCTCCGTTCATATTCGTGTGGAGAAACTCTCATCCTATGAAGTTGAAAAAAATC
AGAATTATCGTTTTGCTCATCTTAAAGTGTTATGCTTTGACGAAAACAGACTGCAACTGGAATCCATTACCAATGGCTTA
GGTCATTGGGGCATACAGTGCACTACTGTCAATGCCTTTGACAAATTAGCCAAAGCCTTAGAGCATAATAAAAACTGCGA
TTTCGCCTTTATTAACGTCAAACAAGGATATGAAGCGCAGATTGCCGATCTTCTCAAAGCTCACCCGAATAAAACTTACA
TTCTTGTTTCAAAATGGCCAATTGCGGATGTCAAATCCTTCGGCGCACAAGTTTTTTTATACCAACCCATTAGCATTCAG
AAACTTCATGACATTATTGAATCCCTAATGCATCAACCATCAGTCCCCCCTTCGCTTGTGCCTCAGGAAGTTGAAAATTT
AAGAGAACAACTGAGATTTTCTCATCCTGATATCCTGATAGCGGAAGATAATCCGGTCAACCGTATGTTGTTAAACTCCT
TGCTCGGTGAAAATGCAAATATGGAATCAGTAAGTGATGGTGAGCAAGCAGTCGTAATCTGTAATGAAAAACGTTTCCAG
GTCATTCTCCTCGATCTGCAAATGCCAAAGCTCAACGGACTTGAAGCTGCCAAAAAAATTCGACATGAATCTTTACTCAA
TCGTCATACGCCTATTCTTTTATTAAGCGCCAGCAGTACCGATATTAACCGCGATAAATTAAAAAATGCCGGTATTGATC
ATTGCCTGCATAAGCCTGTTGAGGAAAAACAACTCATCAGTCATTTACTTCGTTTGATGGACAAGGCTCAACACGCAGCC
ATTGATTGGTCCTTATGCGTGCAGAAACTGTCCGGTAACCAGAAGCTCGCTGAAGATTTTCTCGCCCGTTTTGTAGAAGA
ATTAAAAAAAGACCGGCTTGAATTGATTCAGTTGATGCGCGACAAAAACATTCGTGGTCTTGCCAGTGCCGCACACAAAT
TACATGGGGCCTGCAGTTTCTGTGGCGTTCCTATGTTGCAGAAAAAAGTAAGGGAATTTGAAATCATGACCCAGCAGGTC
AAAAATTCAGAAGATTTACGCTCACTTTTCGCTGAATTAGTCCAGCGTATTGACGCCGTTATTGATGAATATGAAAATTA
TTACAGCGAACCTTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Hpt domain (Hpt) (820-900)

• Single cache domain 4 (sCache_4) (35-179)

• Response regulator receiver domain (Response_reg) (678-788)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	71.209	99.89	0.711