Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   G5S48_RS09100 Genome accession   NZ_CP048915
Coordinates   1907394..1908050 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1902394..1913050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G5S48_RS09070 (G5S48_09020) dcyD 1903273..1904259 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  G5S48_RS09075 (G5S48_09025) tcyL 1904274..1904942 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  G5S48_RS09080 (G5S48_09030) tcyN 1904939..1905691 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  G5S48_RS09085 (G5S48_09035) sdiA 1905921..1906643 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  G5S48_RS09090 (G5S48_09040) yecF 1906711..1906935 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  G5S48_RS09095 (G5S48_09045) yecU 1906922..1907098 (-) 177 WP_000590347.1 protein YecU -
  G5S48_RS24630 - 1907181..1907252 (-) 72 Protein_1780 transcriptional regulator -
  G5S48_RS09100 (G5S48_09050) letA 1907394..1908050 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  G5S48_RS09105 (G5S48_09055) uvrC 1908047..1909879 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  G5S48_RS09110 (G5S48_09060) pgsA 1909936..1910484 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  G5S48_RS09130 (G5S48_09080) yecA 1911134..1911799 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=371573 G5S48_RS09100 WP_000611335.1 1907394..1908050(+) (letA) [Escherichia coli strain E2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=371573 G5S48_RS09100 WP_000611335.1 1907394..1908050(+) (letA) [Escherichia coli strain E2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment