Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   G3T49_RS02525 Genome accession   NZ_CP048756
Coordinates   486563..488365 (-) Length   600 a.a.
NCBI ID   WP_167843176.1    Uniprot ID   -
Organism   Campylobacter jejuni strain ZS006     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 481563..493365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3T49_RS02500 (G3T49_02485) - 481688..482887 (+) 1200 WP_167843173.1 MFS transporter -
  G3T49_RS02505 (G3T49_02490) ciaC 482943..483263 (+) 321 WP_167843174.1 invasion antigen CiaC -
  G3T49_RS02510 (G3T49_02495) hemE 483447..484469 (+) 1023 WP_002859305.1 uroporphyrinogen decarboxylase -
  G3T49_RS02515 (G3T49_02500) - 484466..485368 (+) 903 WP_002934729.1 radical SAM protein -
  G3T49_RS02520 (G3T49_02505) - 485365..486561 (-) 1197 WP_167843175.1 hypothetical protein -
  G3T49_RS02525 (G3T49_02510) uvrC 486563..488365 (-) 1803 WP_167843176.1 excinuclease ABC subunit UvrC Machinery gene
  G3T49_RS02530 (G3T49_02515) - 488358..488852 (-) 495 WP_167843177.1 hypothetical protein -
  G3T49_RS02535 (G3T49_02520) guaA 488991..490526 (+) 1536 WP_167843178.1 glutamine-hydrolyzing GMP synthase -
  G3T49_RS02540 (G3T49_02525) - 490611..492071 (+) 1461 WP_167843179.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69640.68 Da        Isoelectric Point: 9.3794

>NTDB_id=370314 G3T49_RS02525 WP_167843176.1 486563..488365(-) (uvrC) [Campylobacter jejuni strain ZS006]
MTKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETAHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
VSCKSPCIFYQISRCLAPCDKRISKEKYLEILDEAMHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIATIKDLEV
RVEIDIAKLEDFEVFALAFENSMLSTLRFVVQNGKIISANSKIVPIKNDIQWDKNEIYKQLILENFSMDIPLLASVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLAMLVGKKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=370314 G3T49_RS02525 WP_167843176.1 486563..488365(-) (uvrC) [Campylobacter jejuni strain ZS006]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTGCTGGAGTGTATCAATACTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGCGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTACTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCACTTTATTTATACTATCCTTTAAAGCAAAAA
GTAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCACCTTGTGATAAACGCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCACTTTTAAATCCTAGCGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTACGAAGAAGCAGCTAAAGTAAGGGATCAGATTGCAACGATTAAAGATTTGGAAGTT
AGAGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTGTTTGCTTTAGCTTTTGAAAATTCTATGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTGTTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGTATGGACATTCCTTTACTTGCAAGTGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCCTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGAGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTAGGCAAGAAAGCGGCACAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrB/uvrC motif (UVR)

(205-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.251

97

0.458

Multiple sequence alignment