Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   G3M73_RS18185 Genome accession   NZ_CP048605
Coordinates   3887900..3888559 (-) Length   219 a.a.
NCBI ID   WP_001221486.1    Uniprot ID   -
Organism   Escherichia coli strain PapRG-06-5     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3882900..3893559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M73_RS18160 (G3M73_18160) - 3883642..3884589 (+) 948 WP_032281609.1 iron-siderophore ABC transporter substrate-binding protein -
  G3M73_RS18165 (G3M73_18165) - 3884586..3885473 (+) 888 WP_000614954.1 MurR/RpiR family transcriptional regulator -
  G3M73_RS18170 (G3M73_18170) ygiN 3885518..3885832 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  G3M73_RS18175 (G3M73_18175) mdaB 3885863..3886444 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  G3M73_RS18180 (G3M73_18180) qseC 3886554..3887903 (-) 1350 WP_000673365.1 quorum sensing histidine kinase QseC -
  G3M73_RS18185 (G3M73_18185) ciaR 3887900..3888559 (-) 660 WP_001221486.1 quorum sensing response regulator transcription factor QseB Regulator
  G3M73_RS18190 (G3M73_18190) ygiW 3888711..3889103 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  G3M73_RS18195 (G3M73_18195) ygiV 3889156..3889638 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  G3M73_RS18200 (G3M73_18200) ygiS 3889747..3891354 (+) 1608 WP_137537819.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=369980 G3M73_RS18185 WP_001221486.1 3887900..3888559(-) (ciaR) [Escherichia coli strain PapRG-06-5]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=369980 G3M73_RS18185 WP_001221486.1 3887900..3888559(-) (ciaR) [Escherichia coli strain PapRG-06-5]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment