Detailed information NTG0369852

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: D073_RS16700
• Genome accession: NZ_CP041145
• Coordinates: 3368782..3369945 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain At1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3363782..3374945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D073_RS16670 (D073_3158)	-	3364046..3364465 (-)	420	WP_007407479.1	TIGR03826 family flagellar region protein	-
D073_RS16675	comFC	3364539..3365228 (-)	690	WP_197538283.1	phosphoribosyltransferase family protein	Machinery gene
D073_RS16680 (D073_3160)	-	3365234..3365518 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
D073_RS16685 (D073_3161)	comFA	3365576..3366961 (-)	1386	WP_020956417.1	DEAD/DEAH box helicase	Machinery gene
D073_RS16690 (D073_3162)	-	3367070..3367918 (-)	849	WP_007407483.1	DegV family protein	-
D073_RS16695 (D073_3163)	degU	3368016..3368705 (-)	690	WP_020956418.1	two-component system response regulator DegU	Regulator
D073_RS16700 (D073_3164)	degS	3368782..3369945 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
D073_RS16705 (D073_3165)	-	3370168..3370815 (+)	648	WP_007614107.1	YigZ family protein	-
D073_RS16710 (D073_3166)	-	3370820..3372040 (+)	1221	WP_020956419.1	LCP family protein	-
D073_RS16715 (D073_3167)	-	3372147..3373223 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
D073_RS16720 (D073_3168)	tuaH	3373356..3374552 (-)	1197	WP_007407487.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=369852 D073_RS16700 WP_007407484.1 3368782..3369945(-) (degS) [Bacillus velezensis strain At1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=369852 D073_RS16700 WP_007407484.1 3368782..3369945(-) (degS) [Bacillus velezensis strain At1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951