Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   G3M71_RS09405 Genome accession   NZ_CP048603
Coordinates   1995692..1996348 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ChlosBP-23-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1990692..2001348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M71_RS09375 (G3M71_09375) dcyD 1991571..1992557 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  G3M71_RS09380 (G3M71_09380) tcyL 1992572..1993240 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  G3M71_RS09385 (G3M71_09385) tcyN 1993237..1993989 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  G3M71_RS09390 (G3M71_09390) sdiA 1994219..1994941 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  G3M71_RS09395 (G3M71_09395) yecF 1995009..1995233 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  G3M71_RS09400 (G3M71_09400) yecU 1995220..1995396 (-) 177 WP_001307856.1 protein YecU -
  G3M71_RS09405 (G3M71_09405) letA 1995692..1996348 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  G3M71_RS09410 (G3M71_09410) uvrC 1996345..1998177 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  G3M71_RS09415 (G3M71_09415) pgsA 1998234..1998782 (+) 549 WP_163388542.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  G3M71_RS09435 (G3M71_09435) yecA 1999431..2000096 (+) 666 WP_163388543.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=369795 G3M71_RS09405 WP_000611328.1 1995692..1996348(+) (letA) [Escherichia coli strain ChlosBP-23-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=369795 G3M71_RS09405 WP_000611328.1 1995692..1996348(+) (letA) [Escherichia coli strain ChlosBP-23-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTAACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment