Detailed information NTG0369702

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: D069_RS17385
• Genome accession: NZ_CP041143
• Coordinates: 3456818..3457981 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UCMB5007
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3451818..3462981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D069_RS17355 (D069_3240)	-	3452082..3452501 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
D069_RS17360 (D069_3241)	comFC	3452576..3453265 (-)	690	WP_199791910.1	phosphoribosyltransferase family protein	Machinery gene
D069_RS17365 (D069_3242)	-	3453271..3453555 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
D069_RS17370 (D069_3243)	comFA	3453613..3454998 (-)	1386	WP_105937245.1	DEAD/DEAH box helicase	Machinery gene
D069_RS17375 (D069_3244)	-	3455106..3455954 (-)	849	WP_105937244.1	DegV family protein	-
D069_RS17380 (D069_3245)	degU	3456052..3456741 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
D069_RS17385 (D069_3246)	degS	3456818..3457981 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
D069_RS17390 (D069_3247)	-	3458204..3458851 (+)	648	WP_007614107.1	YigZ family protein	-
D069_RS17395 (D069_3248)	-	3458856..3460076 (+)	1221	WP_105937243.1	LCP family protein	-
D069_RS17400 (D069_3249)	-	3460175..3461251 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
D069_RS17405 (D069_3250)	-	3461384..3462580 (-)	1197	WP_105937242.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=369702 D069_RS17385 WP_007407484.1 3456818..3457981(-) (degS) [Bacillus velezensis strain UCMB5007]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=369702 D069_RS17385 WP_007407484.1 3456818..3457981(-) (degS) [Bacillus velezensis strain UCMB5007]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTAGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAAAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTGGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951