Detailed information NTG0368673

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FIU14_RS12690
• Genome accession: NZ_CP040998
• Coordinates: 2525755..2526798 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_773
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2520755..2531798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU14_RS12655 (FIU14_12655)	-	2521125..2521235 (+)	111	WP_001790257.1	hypothetical protein	-
FIU14_RS12660 (FIU14_12660)	-	2521264..2521677 (+)	414	WP_001549145.1	hypothetical protein	-
FIU14_RS12670 (FIU14_12670)	-	2522167..2523153 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
FIU14_RS12675 (FIU14_12675)	map	2523681..2524439 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FIU14_RS12680 (FIU14_12680)	-	2524656..2525042 (+)	387	WP_001110179.1	hypothetical protein	-
FIU14_RS12685 (FIU14_12685)	liaF	2525057..2525758 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FIU14_RS12690 (FIU14_12690)	vraS	2525755..2526798 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FIU14_RS12695 (FIU14_12695)	vraR	2526788..2527417 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
FIU14_RS12700 (FIU14_12700)	-	2527533..2528750 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FIU14_RS12705 (FIU14_12705)	-	2529028..2529303 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
FIU14_RS12710 (FIU14_12710)	-	2529310..2529774 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FIU14_RS12715 (FIU14_12715)	-	2529921..2530121 (+)	201	WP_000180461.1	DUF1128 family protein	-
FIU14_RS12720 (FIU14_12720)	-	2530124..2531380 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=368673 FIU14_RS12690 WP_001017131.1 2525755..2526798(+) (vraS) [Staphylococcus aureus strain FDAARGOS_773]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=368673 FIU14_RS12690 WP_001017131.1 2525755..2526798(+) (vraS) [Staphylococcus aureus strain FDAARGOS_773]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1