Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   FHQ07_RS05765 Genome accession   NZ_CP040871
Coordinates   1184792..1185655 (+) Length   287 a.a.
NCBI ID   WP_139715910.1    Uniprot ID   A0A5B7ZPK8
Organism   Thermomonas aquatica strain SY21     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1175681..1191728 1184792..1185655 within 0


Gene organization within MGE regions


Location: 1175681..1191728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHQ07_RS05720 (FHQ07_05720) - 1175681..1176859 (+) 1179 WP_139715903.1 class I SAM-dependent methyltransferase -
  FHQ07_RS14315 - 1176868..1177410 (+) 543 WP_168191471.1 GNAT family protein -
  FHQ07_RS05730 (FHQ07_05730) - 1177407..1178147 (+) 741 WP_139715904.1 WbqC family protein -
  FHQ07_RS05735 (FHQ07_05735) - 1178119..1178853 (+) 735 WP_240703555.1 CmcI family methyltransferase -
  FHQ07_RS05740 (FHQ07_05740) - 1178893..1179783 (+) 891 WP_139715905.1 glycosyltransferase family A protein -
  FHQ07_RS05745 (FHQ07_05745) - 1179783..1180772 (+) 990 WP_139715906.1 hypothetical protein -
  FHQ07_RS05750 (FHQ07_05750) - 1180769..1181650 (-) 882 WP_139715907.1 glycosyltransferase family 2 protein -
  FHQ07_RS05755 (FHQ07_05755) pilB 1181772..1183490 (+) 1719 WP_139715908.1 type IV-A pilus assembly ATPase PilB Machinery gene
  FHQ07_RS05760 (FHQ07_05760) pilC 1183502..1184773 (+) 1272 WP_139715909.1 type II secretion system F family protein Machinery gene
  FHQ07_RS05765 (FHQ07_05765) pilD 1184792..1185655 (+) 864 WP_139715910.1 A24 family peptidase Machinery gene
  FHQ07_RS05770 (FHQ07_05770) coaE 1185676..1186299 (+) 624 WP_139715911.1 dephospho-CoA kinase -
  FHQ07_RS05775 (FHQ07_05775) - 1186350..1187312 (-) 963 WP_139715912.1 Nudix family hydrolase -
  FHQ07_RS05780 (FHQ07_05780) secA 1187371..1190097 (-) 2727 WP_139715913.1 preprotein translocase subunit SecA -
  FHQ07_RS05785 (FHQ07_05785) - 1190244..1191200 (-) 957 WP_240703556.1 M23 family metallopeptidase -
  FHQ07_RS14660 - 1191225..1191728 (+) 504 WP_338419631.1 DciA family protein -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 31338.28 Da        Isoelectric Point: 8.6952

>NTDB_id=367750 FHQ07_RS05765 WP_139715910.1 1184792..1185655(+) (pilD) [Thermomonas aquatica strain SY21]
MAYLDAHPGLGCPAAAGLGLLVGSFLNVVILRLPRRLEWQWKRDAREILGEPELYDPPPPGIVVERSHCPHCGHQLSWYE
NIPLLSWLALGGKCRSCKAPISFQYPLVELLTGLLFMACVWKFGFGWKGFGAMLLTGLLVAMSGIDLRTRLLPDQLTLPL
MWLGFVASIENLYVGQKAALLGAMAGYLSLWSVYWLFKQLTGKEGMGHGDFKLLAALGAWTGLAGILPTVLISSLVGAVI
GSVWLAMKGKDTATPIPFGPYLAIAGWITFFWGRDLVGMYMRFAGLA

Nucleotide


Download         Length: 864 bp        

>NTDB_id=367750 FHQ07_RS05765 WP_139715910.1 1184792..1185655(+) (pilD) [Thermomonas aquatica strain SY21]
ATGGCTTACCTTGATGCGCACCCCGGCCTCGGCTGCCCCGCCGCGGCCGGACTCGGGCTGCTGGTCGGCAGCTTCCTCAA
CGTGGTGATCCTGCGCCTGCCGAGGCGGCTCGAGTGGCAGTGGAAACGCGACGCCCGCGAGATCCTGGGGGAGCCCGAGC
TGTACGACCCGCCACCGCCCGGCATCGTGGTCGAGCGCTCGCATTGCCCGCACTGCGGGCACCAGCTGTCCTGGTACGAG
AACATCCCGCTGCTCAGCTGGCTGGCCCTGGGCGGCAAGTGCCGCAGCTGCAAGGCGCCGATTTCGTTCCAGTATCCGTT
GGTCGAACTGCTGACCGGCTTGCTGTTCATGGCCTGCGTCTGGAAGTTCGGTTTCGGCTGGAAGGGATTCGGCGCGATGT
TGCTGACCGGCCTGCTGGTCGCGATGTCCGGGATCGACCTGCGCACCCGGCTGCTCCCGGACCAGCTCACCCTGCCCCTG
ATGTGGCTGGGTTTCGTCGCCTCGATCGAGAACCTATACGTCGGCCAGAAGGCCGCGCTGCTGGGCGCGATGGCCGGTTA
CCTGAGCCTGTGGTCGGTGTACTGGCTGTTCAAGCAGCTCACCGGCAAGGAAGGCATGGGCCATGGCGATTTCAAGCTGC
TCGCTGCGCTCGGTGCGTGGACGGGGCTGGCCGGGATACTCCCGACGGTGCTGATCTCGTCGCTGGTCGGTGCGGTGATC
GGCTCGGTCTGGCTGGCGATGAAGGGCAAGGACACGGCGACGCCGATCCCGTTCGGGCCGTACCTGGCCATCGCCGGCTG
GATCACCTTCTTCTGGGGCAGGGACCTGGTCGGCATGTACATGCGCTTCGCCGGGCTCGCCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(18-123)

Type IV leader peptidase family (Peptidase_A24)

(133-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7ZPK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Vibrio cholerae strain A1552

49.462

97.213

0.481
  pilD Vibrio campbellii strain DS40M4

47.535

98.955

0.47
  pilD Acinetobacter baumannii D1279779

45.455

95.819

0.436
  pilD Acinetobacter nosocomialis M2

46.097

93.728

0.432
  pilD Neisseria gonorrhoeae MS11

45.018

94.425

0.425

Multiple sequence alignment