Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FGL66_RS06660 Genome accession   NZ_CP040781
Coordinates   1357966..1358595 (-) Length   209 a.a.
NCBI ID   WP_180809068.1    Uniprot ID   A0A7H9DLW4
Organism   Staphylococcus sp. 17KM0847     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1352966..1363595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL66_RS06630 (FGL66_06590) - 1353262..1354494 (-) 1233 WP_180809062.1 aminopeptidase -
  FGL66_RS06635 (FGL66_06595) - 1354522..1354728 (-) 207 WP_180809063.1 DUF1128 domain-containing protein -
  FGL66_RS06640 (FGL66_06600) - 1354862..1355317 (+) 456 WP_180809064.1 low molecular weight protein-tyrosine-phosphatase -
  FGL66_RS06645 (FGL66_06605) - 1355324..1355614 (+) 291 WP_180809065.1 YtxH domain-containing protein -
  FGL66_RS06650 (FGL66_06610) - 1355870..1357132 (+) 1263 WP_180809066.1 YihY/virulence factor BrkB family protein -
  FGL66_RS06655 (FGL66_06615) - 1357338..1357910 (+) 573 WP_180809067.1 carbonic anhydrase -
  FGL66_RS06660 (FGL66_06620) vraR 1357966..1358595 (-) 630 WP_180809068.1 response regulator transcription factor Regulator
  FGL66_RS06665 (FGL66_06625) vraS 1358585..1359628 (-) 1044 WP_180809069.1 sensor histidine kinase Regulator
  FGL66_RS06670 (FGL66_06630) liaF 1359625..1360326 (-) 702 WP_180809070.1 cell wall-active antibiotics response protein LiaF -
  FGL66_RS06675 (FGL66_06635) - 1360339..1360728 (-) 390 WP_180809071.1 hypothetical protein -
  FGL66_RS06680 (FGL66_06640) map 1360827..1361588 (-) 762 WP_180809072.1 type I methionyl aminopeptidase -
  FGL66_RS06685 (FGL66_06645) - 1361684..1362691 (+) 1008 WP_180809073.1 aromatic acid exporter family protein -
  FGL66_RS06690 (FGL66_06650) - 1362964..1363362 (+) 399 WP_180809074.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23454.14 Da        Isoelectric Point: 5.3555

>NTDB_id=367100 FGL66_RS06660 WP_180809068.1 1357966..1358595(-) (vraR) [Staphylococcus sp. 17KM0847]
MTIKVLFVDDHEMVRIGISSYLSTQVDIEVVGEGSSGREAIEKAHELHPDVILMDLVMTDMDGVEATTQIKKALPHIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIAKAIRKTSLGESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=367100 FGL66_RS06660 WP_180809068.1 1357966..1358595(-) (vraR) [Staphylococcus sp. 17KM0847]
ATGACGATTAAAGTATTATTTGTAGATGATCATGAAATGGTTCGAATTGGTATTTCTAGCTATTTATCTACTCAAGTTGA
TATTGAAGTAGTAGGCGAAGGGAGTTCTGGAAGAGAGGCGATTGAGAAGGCACATGAATTACATCCAGATGTTATTTTGA
TGGATTTGGTCATGACTGATATGGACGGTGTAGAAGCAACGACACAAATAAAAAAAGCATTACCACATATTAAAGTTGTA
ATGTTAACAAGTTACATAGAAGATAAAGAAGTCTATCGTGCATTGGATGCAGGTGTAGATAGTTATATTTTGAAAACAAC
CAGTGCAAGTGATATTGCTAAAGCGATTCGTAAAACAAGTTTAGGTGAATCTGTGTTTGAAGCGGAAGTACTTGTGAAAA
TGCGTAACCGTATGAAACAGCGAGCGGAGTTATATGAGATGTTAACCGAAAGAGAAATGGAGATTCTACTTTTAATTGCT
AAAGGTTATTCTAATCAAGAGATTGCAAGTGCTTCTCATATTACAATCAAAACCGTTAAAACACATGTAAGTAATATTTT
AAGTAAGTTGGAAGTTCAAGATAGGACACAAGCTGTCATTTATGCATTTCAACATGGTTTAATAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H9DLW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment