Detailed information NTG0367101

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FGL66_RS06665
• Genome accession: NZ_CP040781
• Coordinates: 1358585..1359628 (-)
• Length: 347 a.a.
• NCBI ID: WP_180809069.1
• Uniprot ID: A0A7H9DLT0
• Organism: Staphylococcus sp. 17KM0847
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1353585..1364628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL66_RS06635 (FGL66_06595)	-	1354522..1354728 (-)	207	WP_180809063.1	DUF1128 domain-containing protein	-
FGL66_RS06640 (FGL66_06600)	-	1354862..1355317 (+)	456	WP_180809064.1	low molecular weight protein-tyrosine-phosphatase	-
FGL66_RS06645 (FGL66_06605)	-	1355324..1355614 (+)	291	WP_180809065.1	YtxH domain-containing protein	-
FGL66_RS06650 (FGL66_06610)	-	1355870..1357132 (+)	1263	WP_180809066.1	YihY/virulence factor BrkB family protein	-
FGL66_RS06655 (FGL66_06615)	-	1357338..1357910 (+)	573	WP_180809067.1	carbonic anhydrase	-
FGL66_RS06660 (FGL66_06620)	vraR	1357966..1358595 (-)	630	WP_180809068.1	response regulator transcription factor	Regulator
FGL66_RS06665 (FGL66_06625)	vraS	1358585..1359628 (-)	1044	WP_180809069.1	sensor histidine kinase	Regulator
FGL66_RS06670 (FGL66_06630)	liaF	1359625..1360326 (-)	702	WP_180809070.1	cell wall-active antibiotics response protein LiaF	-
FGL66_RS06675 (FGL66_06635)	-	1360339..1360728 (-)	390	WP_180809071.1	hypothetical protein	-
FGL66_RS06680 (FGL66_06640)	map	1360827..1361588 (-)	762	WP_180809072.1	type I methionyl aminopeptidase	-
FGL66_RS06685 (FGL66_06645)	-	1361684..1362691 (+)	1008	WP_180809073.1	aromatic acid exporter family protein	-
FGL66_RS06690 (FGL66_06650)	-	1362964..1363362 (+)	399	WP_180809074.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40091.33 Da
• Isoelectric Point: 5.2712

>NTDB_id=367101 FGL66_RS06665 WP_180809069.1 1358585..1359628(-) (vraS) [Staphylococcus sp. 17KM0847]
MNHYFRTIGAMLILVYAMFTAFFFIDKVFVNIIFFQGMFYKQIFGVPVFLFINLLVVFLCILVGSVIAYKINQQYDWLQE
QIERAIEGETVGINDHQIELYHETIALYQTLVPLNQELHKLRIKTQNLTNEQYNMNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLNQQIPTLEKMIQDSQLEMRALLLHLRPIGLNDRTLGEGIESLVTDLQRKVPMKVIYEI
DAFEVPKGIEDHLFRITQEAISNTLRHANGTQVSVELLNREGYLLLRIQDDGVGFNVDDKIEQSYGLKNMRERATEIGAT
FHIVSLPDSGTRIEVKAPLDKEGHYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=367101 FGL66_RS06665 WP_180809069.1 1358585..1359628(-) (vraS) [Staphylococcus sp. 17KM0847]
ATGAATCACTATTTTCGTACAATTGGCGCGATGTTAATACTTGTTTATGCGATGTTTACAGCTTTTTTCTTTATAGATAA
AGTTTTTGTTAATATTATTTTCTTTCAAGGGATGTTTTATAAGCAAATTTTTGGTGTGCCTGTATTTTTGTTTATTAATT
TACTTGTCGTTTTTTTGTGTATTCTTGTAGGAAGTGTAATTGCTTATAAAATTAATCAACAATATGATTGGTTACAAGAG
CAAATTGAACGTGCTATCGAAGGTGAGACGGTAGGTATTAATGATCACCAAATCGAACTATACCATGAAACCATTGCTTT
ATATCAAACACTAGTACCATTAAATCAAGAGCTGCATAAACTTCGTATCAAAACACAAAATTTAACAAATGAACAATATA
ATATGAATGATTTGAAAGTGAAAAAAATTATTGAAGATGAACGTCAACGTTTGGCACGAGAGTTACATGATAGTGTATCT
CAACAGTTATTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACCAAGTTAGAAGCACCTTTGAATCAGCAAATACC
GACATTGGAGAAGATGATTCAAGATTCTCAATTAGAAATGCGTGCGTTATTATTGCATTTGAGACCGATTGGTTTAAATG
ATAGGACACTAGGTGAAGGGATTGAATCATTGGTTACAGATCTCCAACGTAAAGTGCCGATGAAAGTCATATATGAAATT
GATGCATTCGAAGTGCCCAAAGGGATTGAAGATCATTTATTCCGTATCACACAAGAAGCCATTTCAAATACGTTGAGACA
TGCTAATGGTACACAAGTCAGTGTAGAATTATTAAATAGAGAAGGGTATTTATTATTGCGTATTCAAGATGACGGTGTAG
GTTTTAATGTAGATGATAAGATAGAACAGAGTTATGGTTTGAAAAATATGAGAGAGCGGGCCACAGAAATTGGTGCCACT
TTTCATATCGTATCACTACCTGACTCTGGCACACGTATTGAAGTAAAGGCACCTTTAGATAAGGAGGGACATTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A7H9DLT0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	81.268	100	0.813