Detailed information NTG0036684

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MRUB_RS10515
• Genome accession: NC_013946
• Coordinates: 2121619..2122632 (+)
• Length: 337 a.a.
• NCBI ID: WP_013014335.1
• Uniprot ID: D3PTQ4
• Organism: Meiothermus ruber DSM 1279
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2116619..2127632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MRUB_RS10485 (Mrub_2077)	-	2116992..2117960 (-)	969	WP_013014329.1	TRAP transporter substrate-binding protein	-
MRUB_RS10490 (Mrub_2078)	-	2117970..2118782 (-)	813	WP_013014330.1	IclR family transcriptional regulator	-
MRUB_RS10495 (Mrub_2079)	-	2118868..2119845 (-)	978	WP_013014331.1	deoxyhypusine synthase family protein	-
MRUB_RS10500 (Mrub_2080)	-	2120039..2120458 (+)	420	WP_244403977.1	group III truncated hemoglobin	-
MRUB_RS10505 (Mrub_2081)	-	2120430..2120651 (-)	222	WP_013014333.1	DUF2905 domain-containing protein	-
MRUB_RS10510 (Mrub_2082)	era	2120655..2121569 (-)	915	WP_015586807.1	GTPase Era	-
MRUB_RS10515 (Mrub_2083)	dprA	2121619..2122632 (+)	1014	WP_013014335.1	DNA-processing protein DprA	Machinery gene
MRUB_RS10520 (Mrub_2084)	dusA	2122617..2123636 (-)	1020	WP_013014336.1	tRNA dihydrouridine(20/20a) synthase DusA	-
MRUB_RS10525 (Mrub_2085)	ispH	2123633..2124661 (-)	1029	WP_013014337.1	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	-
MRUB_RS10530 (Mrub_2086)	-	2124715..2126223 (-)	1509	WP_013014338.1	carboxypeptidase M32	-

Sequence

Protein

• Length: 337 a.a.
• Molecular weight: 35454.73 Da
• Isoelectric Point: 5.0744

>NTDB_id=36684 MRUB_RS10515 WP_013014335.1 2121619..2122632(+) (dprA) [Meiothermus ruber DSM 1279]
MPDPLALALTPQIGPQRLQQALPTDLSVEAVADVLGPEIAAGYARTLQSGLAEQERAQAARLGVRLIGLWEEDYPEVLRH
LESPPTVLYLKGELPPSERNIGIVGTRKASPWATAWTHKVARELAEAGIGIISGLALGIDAAAHKGALDGGGYTLGVLGS
AIDHFYPAQNRALAERMSVLSEFPLGTPPQAGLFPRRNRIVAAFSRAVLVVEAGEKSGSLITAKFAAELGRDVLAVPGRP
GDTFSLGCNRLIQDGAGLVLNTEDVLNALGMLAPKKQAVQLEGSEAKVYRALLELPEALPDDLAQSTGLSTGEVLSVLMM
LELKGLVQSSAGRYSPA

Nucleotide

• Length: 1014 bp

>NTDB_id=36684 MRUB_RS10515 WP_013014335.1 2121619..2122632(+) (dprA) [Meiothermus ruber DSM 1279]
ATGCCCGATCCCCTGGCCCTTGCGCTCACTCCCCAGATTGGCCCCCAGCGCCTGCAGCAAGCCCTCCCAACCGACCTGAG
CGTGGAGGCTGTGGCCGATGTGCTGGGCCCGGAAATTGCAGCAGGCTATGCCAGAACCCTTCAGAGCGGCCTGGCCGAAC
AGGAGCGCGCACAGGCAGCCCGGTTGGGGGTGCGGCTGATCGGGCTCTGGGAGGAGGACTACCCAGAGGTGCTCCGGCAT
CTGGAGAGCCCGCCTACGGTGCTGTACCTGAAAGGGGAGCTGCCTCCTTCCGAGCGCAACATCGGAATTGTGGGCACCCG
CAAGGCCAGCCCCTGGGCTACCGCCTGGACGCACAAAGTAGCCCGCGAGCTGGCCGAGGCTGGCATCGGGATCATCTCGG
GGCTGGCTCTGGGCATAGATGCCGCCGCACACAAAGGGGCCCTGGACGGGGGCGGCTATACCCTGGGGGTGCTGGGCAGC
GCCATAGACCACTTCTATCCGGCCCAGAACCGCGCCCTGGCCGAGAGGATGAGCGTACTCTCGGAGTTCCCACTGGGCAC
CCCCCCACAGGCCGGGTTGTTTCCCCGGCGCAACCGGATCGTGGCGGCCTTCTCCAGGGCGGTGCTGGTGGTGGAGGCCG
GAGAAAAAAGCGGCAGTCTGATTACCGCCAAGTTTGCAGCAGAGCTGGGCCGCGATGTGCTGGCCGTACCGGGCCGGCCC
GGCGATACTTTTTCGCTGGGCTGCAACCGGCTGATTCAGGACGGAGCCGGGCTGGTGCTGAACACCGAGGACGTGCTGAA
CGCCCTGGGGATGCTGGCCCCCAAAAAGCAGGCCGTGCAGTTGGAGGGAAGCGAGGCCAAAGTCTACCGGGCCTTGCTCG
AGCTCCCCGAGGCCCTGCCCGACGACCTCGCGCAGAGCACCGGCCTTTCCACTGGCGAGGTTCTCTCGGTGCTGATGATG
CTCGAGCTTAAGGGACTGGTGCAGAGCAGCGCAGGGCGCTACAGCCCGGCGTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (276-332)

• DNA recombination-mediator protein A (DNA_processg_A) (60-260)

3D structure

• AlphaFold DB: D3PTQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Thermus thermophilus HB27	55.522	99.407	0.552
dprA	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	48.288	86.647	0.418
dprA	Glaesserella parasuis strain SC1401	35.068	100	0.38