NTDB

Overview

Name	cclA/cilC	Type	Machinery gene
Locus tag	GV831_RS11250	Genome accession	NZ_CP047891
Coordinates	2254894..2255559 (-)	Length	221 a.a.
NCBI ID	WP_004254535.1	Uniprot ID	Q9CE22
Organism	Lactococcus lactis subsp. lactis strain WHH2311
Function	processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2249894..2260559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GV831_RS11230 (GV831_11185)	-	2250388..2251518 (+)	1131	WP_014570781.1	aminotransferase	-
GV831_RS11235 (GV831_11190)	-	2251710..2253203 (+)	1494	WP_014570780.1	basic amino acid/polyamine antiporter	-
GV831_RS11240 (GV831_11195)	-	2253282..2253773 (+)	492	WP_010906273.1	prolyl-tRNA synthetase associated domain-containing protein	-
GV831_RS11245 (GV831_11200)	dinB	2253852..2254943 (+)	1092	WP_004254532.1	DNA polymerase IV	-
GV831_RS11250 (GV831_11205)	cclA/cilC	2254894..2255559 (-)	666	WP_004254535.1	A24 family peptidase	Machinery gene
GV831_RS11255 (GV831_11210)	-	2255726..2256172 (+)	447	WP_004254538.1	DNA starvation/stationary phase protection protein	-
GV831_RS11260 (GV831_11215)	-	2256255..2256641 (-)	387	WP_004254540.1	rhodanese-like domain-containing protein	-
GV831_RS11265 (GV831_11220)	-	2256644..2257615 (-)	972	WP_004254542.1	ROK family glucokinase	-
GV831_RS11270 (GV831_11225)	-	2257649..2257870 (-)	222	WP_010906270.1	YqgQ family protein	-
GV831_RS11275 (GV831_11230)	-	2258063..2258791 (+)	729	WP_004254546.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
GV831_RS11280 (GV831_11235)	-	2259091..2259417 (+)	327	WP_004254552.1	lactococcin 972 family bacteriocin	-
GV831_RS11285	-	2259427..2260002 (+)	576	WP_228763129.1	hypothetical protein	-

Sequence

Protein

Download Length: 221 a.a. Molecular weight: 25664.87 Da Isoelectric Point: 8.8481

                                >NTDB_id=366446 GV831_RS11250 WP_004254535.1 2254894..2255559(-) (cclA/cilC) [Lactococcus lactis subsp. lactis strain WHH2311]

MDILFIFLIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSKIPYLYVFLEFSS

ALIFVLAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF

LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide

Download Length: 666 bp

                                >NTDB_id=366446 GV831_RS11250 WP_004254535.1 2254894..2255559(-) (cclA/cilC) [Lactococcus lactis subsp. lactis strain WHH2311]

ATGGACATTTTATTTATATTTTTAATTGGAAGTATTTTTGGCTCCTTTTTTGGCTTAATAGTTGACCGTATTCCACTAAG

AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT

CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTAAAATTCCATATTTATATGTTTTTTTGGAGTTCTCATCA

GCTTTAATTTTTGTTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC

TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC

TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT

TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT

CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT

TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q9CE22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cclA/cilC	Streptococcus mitis SK321	37.9	99.095	0.376
cclA/cilC	Streptococcus pneumoniae Rx1	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae D39	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae R6	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae TIGR4	37.674	97.285	0.367

Detailed information NTG0366446