Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SMUNN2025_RS03150 Genome accession   NC_013928
Coordinates   616461..617813 (+) Length   450 a.a.
NCBI ID   WP_012997648.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 611461..622813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS03120 (SmuNN2025_0582) endA 611481..612362 (+) 882 WP_002264825.1 DNA/RNA non-specific endonuclease Machinery gene
  SMUNN2025_RS03125 (SmuNN2025_0583) - 612430..613080 (-) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUNN2025_RS03130 (SmuNN2025_0584) - 613095..613799 (-) 705 WP_002262933.1 amino acid ABC transporter permease -
  SMUNN2025_RS03135 (SmuNN2025_0585) - 613817..614629 (-) 813 WP_002277521.1 transporter substrate-binding domain-containing protein -
  SMUNN2025_RS03140 (SmuNN2025_0586) - 614626..615408 (-) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  SMUNN2025_RS03145 (SmuNN2025_0587) vicR 615761..616468 (+) 708 WP_002262930.1 response regulator YycF Regulator
  SMUNN2025_RS03150 (SmuNN2025_0588) vicK 616461..617813 (+) 1353 WP_012997648.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUNN2025_RS03155 (SmuNN2025_0589) vicX 617810..618613 (+) 804 WP_012997649.1 MBL fold metallo-hydrolase Regulator
  SMUNN2025_RS03160 (SmuNN2025_0590) rnc 618720..619415 (+) 696 WP_002266141.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51694.37 Da        Isoelectric Point: 4.5212

>NTDB_id=36586 SMUNN2025_RS03150 WP_012997648.1 616461..617813(+) (vicK) [Streptococcus mutans NN2025]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRRGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTVTMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEGEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=36586 SMUNN2025_RS03150 WP_012997648.1 616461..617813(+) (vicK) [Streptococcus mutans NN2025]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACGCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCCGCGGAAAGATTACCGTTATTAATGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCAGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGTTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATTTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTGTAACGATGCAGACAACAGATACACAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAACGATAATGATGCAATTGATGAATGGGAAGAAGGTGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

99.333

100

0.993
  micB Streptococcus pneumoniae Cp1015

67.599

95.333

0.644

Multiple sequence alignment