Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E3S65_RS04240 Genome accession   NZ_CP047859
Coordinates   830538..831311 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain UP_1405     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 825538..836311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S65_RS04205 (E3S65_04205) - 825786..826556 (-) 771 WP_000473699.1 isoprenyl transferase -
  E3S65_RS04210 (E3S65_04210) frr 826929..827483 (-) 555 WP_001280006.1 ribosome recycling factor -
  E3S65_RS04215 (E3S65_04215) pyrH 827502..828224 (-) 723 WP_000057330.1 UMP kinase -
  E3S65_RS04220 (E3S65_04220) tsf 828361..829242 (-) 882 WP_000201392.1 translation elongation factor Ts -
  E3S65_RS04225 (E3S65_04225) - 829277..829390 (-) 114 WP_001789890.1 hypothetical protein -
  E3S65_RS04230 (E3S65_04230) rpsB 829424..830191 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  E3S65_RS04235 (E3S65_04235) - 830390..830464 (-) 75 WP_031761472.1 hypothetical protein -
  E3S65_RS04240 (E3S65_04240) codY 830538..831311 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E3S65_RS04245 (E3S65_04245) hslU 831336..832739 (-) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  E3S65_RS04250 (E3S65_04250) hslV 832805..833350 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E3S65_RS04255 (E3S65_04255) xerC 833347..834243 (-) 897 WP_001015601.1 tyrosine recombinase XerC -
  E3S65_RS04260 (E3S65_04260) trmFO 834661..835968 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=365765 E3S65_RS04240 WP_000055337.1 830538..831311(-) (codY) [Staphylococcus aureus strain UP_1405]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=365765 E3S65_RS04240 WP_000055337.1 830538..831311(-) (codY) [Staphylococcus aureus strain UP_1405]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment