Detailed information NTG0364564

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FE240_RS14155
• Genome accession: NZ_CP040449
• Coordinates: 2985562..2986434 (+)
• Length: 290 a.a.
• NCBI ID: WP_193001828.1
• Uniprot ID: A0A5J6WZM9
• Organism: Aeromonas simiae strain A6
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2980562..2991434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FE240_RS14135 (FE240_14140)	nadC	2980997..2981854 (+)	858	WP_193001823.1	carboxylating nicotinate-nucleotide diphosphorylase	-
FE240_RS14140 (FE240_14145)	-	2982113..2982559 (+)	447	WP_193001825.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
FE240_RS14145 (FE240_14150)	pilB	2982563..2984269 (+)	1707	WP_193001826.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FE240_RS14150 (FE240_14155)	-	2984305..2985543 (+)	1239	Protein_2725	type II secretion system F family protein	-
FE240_RS14155 (FE240_14160)	pilD	2985562..2986434 (+)	873	WP_193001828.1	A24 family peptidase	Machinery gene
FE240_RS14160 (FE240_14165)	coaE	2986447..2987061 (+)	615	WP_193001830.1	dephospho-CoA kinase	-
FE240_RS14165 (FE240_14170)	zapD	2987099..2987821 (+)	723	WP_042045478.1	cell division protein ZapD	-
FE240_RS14170 (FE240_14175)	yacG	2987832..2988023 (+)	192	WP_193001832.1	DNA gyrase inhibitor YacG	-
FE240_RS14175 (FE240_14180)	mutT	2988073..2988477 (-)	405	WP_193001834.1	8-oxo-dGTP diphosphatase MutT	-
FE240_RS14180 (FE240_14185)	secA	2988546..2991254 (-)	2709	WP_193001836.1	preprotein translocase subunit SecA	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 32305.88 Da
• Isoelectric Point: 6.9390

>NTDB_id=364564 FE240_RS14155 WP_193001828.1 2985562..2986434(+) (pilD) [Aeromonas simiae strain A6]
MSTLLLLSQELPWLYFILIALFSLLIGSFLNVVIYRLPIMMERQWQSEYQDYFHPEQEAPSLPRFNLMLPRSACPHCGHA
ITALENIPIISWLALRGRCRGCQAPISPRYPMVEATTALLSLLVAWQLPAGLPLLAGLLITWMLIALTLIDLDKMLLPDE
LTLPLLWVGLLINLGGTLASLEDAVIGAVAGYLLLWSLYWAFKLLTGKEGMGYGDFKLLAALGACLGWQKLPLILMLSAL
LGALVGILLIVLRRHEQGKPIPFGPYLALAGWVALLWGERINHWYLSTLL

Nucleotide

• Length: 873 bp

>NTDB_id=364564 FE240_RS14155 WP_193001828.1 2985562..2986434(+) (pilD) [Aeromonas simiae strain A6]
ATGTCCACTCTCTTGCTACTTAGCCAGGAGCTACCCTGGCTCTATTTTATTCTCATCGCCCTGTTCTCCCTGCTCATTGG
CAGCTTTCTCAATGTGGTGATCTACCGTCTGCCCATCATGATGGAGCGTCAGTGGCAAAGCGAATATCAGGACTACTTTC
ACCCCGAGCAGGAGGCGCCCTCCCTCCCCCGCTTTAATCTGATGCTCCCCCGCTCGGCTTGTCCTCACTGCGGCCATGCC
ATCACGGCGCTCGAAAATATCCCCATCATCAGCTGGCTTGCCCTACGCGGGCGTTGCAGAGGCTGCCAGGCCCCCATCTC
ACCACGTTATCCCATGGTCGAGGCCACCACGGCCCTGCTCTCGCTCTTGGTCGCGTGGCAACTGCCCGCCGGCTTGCCAC
TGTTGGCCGGTCTGCTGATCACCTGGATGCTGATTGCACTGACCCTTATCGATCTCGACAAGATGCTGCTGCCCGATGAA
CTGACGCTCCCCCTGTTGTGGGTCGGCCTGCTCATCAACCTTGGCGGCACCCTGGCCTCGCTGGAAGATGCGGTGATCGG
CGCCGTAGCCGGCTATCTGCTGCTATGGAGCCTCTATTGGGCTTTTAAGCTGCTCACCGGCAAGGAGGGAATGGGCTATG
GCGACTTCAAACTGCTGGCGGCGCTCGGCGCCTGCCTGGGGTGGCAGAAGCTGCCGCTGATTCTGATGCTCTCTGCCCTG
CTGGGGGCTCTGGTGGGGATATTGCTCATCGTGCTGCGCCGTCATGAGCAGGGTAAACCGATCCCCTTTGGTCCCTATCT
GGCGCTGGCCGGTTGGGTCGCCCTACTCTGGGGCGAGCGCATCAACCATTGGTACCTCAGTACCCTGCTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (21-127)

• Type IV leader peptidase family (Peptidase_A24) (139-247)

3D structure

• AlphaFold DB: A0A5J6WZM9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	57.5	96.552	0.555
pilD	Acinetobacter baumannii D1279779	54.48	96.207	0.524
pilD	Acinetobacter nosocomialis M2	54.317	95.862	0.521
pilD	Vibrio campbellii strain DS40M4	52.65	97.586	0.514
pilD	Neisseria gonorrhoeae MS11	47.619	94.138	0.448