Detailed information
Bioinformatically predicted
Overview
| Name | amiA3 | Type | Regulator |
| Locus tag | SMI_RS06605 | Genome accession | NC_013853 |
| Coordinates | 1295060..1297042 (-) | Length | 660 a.a. |
| NCBI ID | WP_000747539.1 | Uniprot ID | D3H9K0 |
| Organism | Streptococcus mitis B6 | ||
| Function | binding to XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1297447..1347914 | 1295060..1297042 | flank | 405 |
| IScluster/Tn | 1297447..1300532 | 1295060..1297042 | flank | 405 |
Gene organization within MGE regions
Location: 1295060..1347914
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SMI_RS06605 (smi_1302) | amiA3 | 1295060..1297042 (-) | 1983 | WP_000747539.1 | peptide ABC transporter substrate-binding protein | Regulator |
| SMI_RS06610 (smi_1303) | - | 1297447..1298613 (-) | 1167 | WP_000163007.1 | IS30-like element ISSmi1 family transposase | - |
| SMI_RS06615 (smi_1304) | - | 1298815..1299828 (+) | 1014 | WP_000665633.1 | lactonase family protein | - |
| SMI_RS06620 (smi_1305) | - | 1300020..1300532 (+) | 513 | Protein_1271 | transposase | - |
| SMI_RS06625 (smi_1306) | - | 1300611..1308035 (-) | 7425 | WP_000527121.1 | YSIRK signal domain/LPXTG anchor domain surface protein | - |
| SMI_RS06630 (smi_1307) | - | 1308460..1308834 (+) | 375 | Protein_1273 | IS30 family transposase | - |
| SMI_RS10565 | - | 1308891..1309092 (-) | 202 | Protein_1274 | hypothetical protein | - |
| SMI_RS06635 (smi_1308) | - | 1309148..1309567 (-) | 420 | WP_000068046.1 | F0F1 ATP synthase subunit epsilon | - |
| SMI_RS06640 (smi_1309) | atpD | 1309578..1310984 (-) | 1407 | WP_000094352.1 | F0F1 ATP synthase subunit beta | - |
| SMI_RS06645 (smi_1310) | - | 1311070..1311948 (-) | 879 | WP_000301214.1 | F0F1 ATP synthase subunit gamma | - |
| SMI_RS06650 (smi_1311) | atpA | 1311964..1313469 (-) | 1506 | WP_000996630.1 | F0F1 ATP synthase subunit alpha | - |
| SMI_RS06655 (smi_1312) | - | 1313484..1314020 (-) | 537 | WP_000359027.1 | F0F1 ATP synthase subunit delta | - |
| SMI_RS06660 (smi_1313) | atpF | 1314020..1314514 (-) | 495 | WP_000558549.1 | F0F1 ATP synthase subunit B | - |
| SMI_RS06665 (smi_1314) | atpB | 1314528..1315241 (-) | 714 | WP_000392858.1 | F0F1 ATP synthase subunit A | - |
| SMI_RS06670 (smi_1315) | - | 1315274..1315474 (-) | 201 | WP_001054559.1 | F0F1 ATP synthase subunit C | - |
| SMI_RS06675 (smi_1316) | - | 1315784..1317070 (-) | 1287 | WP_000169093.1 | peptidase U32 family protein | - |
| SMI_RS10935 (smi_1317) | - | 1317257..1319596 (-) | 2340 | WP_000479259.1 | G5 domain-containing protein | - |
| SMI_RS06685 (smi_1318) | - | 1320479..1322665 (+) | 2187 | WP_000470932.1 | ATP-dependent nuclease | - |
| SMI_RS06690 (smi_1319) | - | 1322662..1324455 (+) | 1794 | WP_000181735.1 | ATP-dependent helicase | - |
| SMI_RS06695 (smi_1320) | - | 1324655..1324969 (+) | 315 | WP_000421279.1 | YdcP family protein | - |
| SMI_RS06700 (smi_1321) | - | 1324990..1325367 (+) | 378 | WP_001234191.1 | YdcP family protein | - |
| SMI_RS06705 (smi_1322) | - | 1325377..1326150 (+) | 774 | WP_000185761.1 | hypothetical protein | - |
| SMI_RS06710 (smi_1323) | - | 1326172..1327575 (+) | 1404 | WP_001130244.1 | FtsK/SpoIIIE domain-containing protein | - |
| SMI_RS06715 (smi_1324) | mobT | 1327757..1328941 (+) | 1185 | WP_000426689.1 | MobT family relaxase | - |
| SMI_RS06720 | - | 1328938..1329228 (+) | 291 | WP_000055376.1 | hypothetical protein | - |
| SMI_RS06725 (smi_1325) | - | 1329225..1329446 (+) | 222 | WP_001009054.1 | hypothetical protein | - |
| SMI_RS06730 (smi_1326) | - | 1329488..1330267 (+) | 780 | WP_000675717.1 | abortive infection family protein | - |
| SMI_RS06735 (smi_1327) | - | 1330328..1330828 (+) | 501 | WP_000425404.1 | antirestriction protein ArdA | - |
| SMI_RS06740 (smi_1328) | - | 1330884..1331522 (+) | 639 | WP_000248477.1 | DUF6037 family protein | - |
| SMI_RS06745 (smi_1329) | - | 1331594..1331989 (+) | 396 | WP_000723887.1 | conjugal transfer protein | - |
| SMI_RS06750 (smi_1330) | - | 1331973..1334426 (+) | 2454 | WP_000331165.1 | ATP-binding protein | - |
| SMI_RS06755 (smi_1331) | - | 1334423..1336450 (+) | 2028 | WP_000192395.1 | CD3337/EF1877 family mobilome membrane protein | - |
| SMI_RS06760 (smi_1332) | - | 1336447..1337469 (+) | 1023 | WP_000768374.1 | bifunctional lytic transglycosylase/C40 family peptidase | - |
| SMI_RS06765 (smi_1333) | - | 1337486..1338415 (+) | 930 | WP_000584387.1 | conjugal transfer protein | - |
| SMI_RS11045 | - | 1338729..1338776 (+) | 48 | Protein_1302 | hypothetical protein | - |
| SMI_RS06775 (smi_1334) | tet(M) | 1338792..1340711 (+) | 1920 | WP_000691748.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| SMI_RS06780 (smi_1335) | - | 1340812..1340997 (+) | 186 | WP_413926387.1 | cysteine-rich KTR domain-containing protein | - |
| SMI_RS06785 (smi_1336) | - | 1341055..1341408 (-) | 354 | WP_001227350.1 | helix-turn-helix domain-containing protein | - |
| SMI_RS06790 (smi_1338) | - | 1341939..1342361 (+) | 423 | WP_000804880.1 | RNA polymerase sigma factor | - |
| SMI_RS06795 (smi_1339) | - | 1342358..1342588 (+) | 231 | WP_000845143.1 | helix-turn-helix domain-containing protein | - |
| SMI_RS06800 (smi_1340) | - | 1343086..1343286 (+) | 201 | WP_000633906.1 | DUF3173 family protein | - |
| SMI_RS06805 (smi_1341) | - | 1343313..1344506 (+) | 1194 | WP_000237797.1 | site-specific integrase | - |
| SMI_RS06810 (smi_1342) | guaA | 1344574..1346136 (-) | 1563 | WP_012972538.1 | glutamine-hydrolyzing GMP synthase | - |
| SMI_RS06815 (smi_1343) | - | 1346278..1346976 (+) | 699 | WP_000936183.1 | GntR family transcriptional regulator | - |
| SMI_RS06820 (smi_1344) | - | 1347018..1347914 (-) | 897 | WP_000071683.1 | DMT family transporter | - |
Sequence
Protein
Download Length: 660 a.a. Molecular weight: 72686.09 Da Isoelectric Point: 5.1116
>NTDB_id=36323 SMI_RS06605 WP_000747539.1 1295060..1297042(-) (amiA3) [Streptococcus mitis B6]
MKKRVFLAAGVAVLSVAVLAACSSGNGNKEATKPVTYTYVFSSDPATLDYTVSGQKSTKQITGNVIDGLLENDQYGNLVP
SVAEDWTVSKDGLTYTYKIRKGIKWYTNEGEEYGEVKAQDFVTGLKHAADKKSEALYLVQDSIKGLDDYVNGKTTDFSTV
GVKATDDYTVVYTLNHPESFWNSKTTMGILAPVSEDFLASKGDDFGKATDVTSILYNGAYLLKGLTSKSSIEMTKNQNYW
DKQNVFIDDIKLSYFDGQDADSLGRGFDEGNYPAAPLFKNSANYERLKEKYKDNIIYSQQQGTTFYISTNIDRVAYNHTA
KTSDVEKSSTKKALLNKDFRQSLAFATDRKAGISQVFGDEVAPRKLRTSLTPPTFVQVGEQSFGQVAKAELDKLDGVWKD
VSLDDAQDSLHNVDKAKTKFEAAKKTLQADGVQFPIHLDIPVSSTRPEFVRQAQSYKQSVEEAIGADNVVVDIQQVSDDE
LASMTVLATSNTNTDWDINANSGWGPDYADPSTYLDIFDPTSGPNLLGSLGVVPGKDSSAIKAVGLDKFKELITDANSEK
TNLEKRYAKYAKAQAWLTDSALVIPVHSDGAQMLVTKKVLGTGAGGWVGDKTSENSYKYLKIQDKIVTTKEMDEFRKKFA
DEKAKSNADYQKNLDRHIQD
MKKRVFLAAGVAVLSVAVLAACSSGNGNKEATKPVTYTYVFSSDPATLDYTVSGQKSTKQITGNVIDGLLENDQYGNLVP
SVAEDWTVSKDGLTYTYKIRKGIKWYTNEGEEYGEVKAQDFVTGLKHAADKKSEALYLVQDSIKGLDDYVNGKTTDFSTV
GVKATDDYTVVYTLNHPESFWNSKTTMGILAPVSEDFLASKGDDFGKATDVTSILYNGAYLLKGLTSKSSIEMTKNQNYW
DKQNVFIDDIKLSYFDGQDADSLGRGFDEGNYPAAPLFKNSANYERLKEKYKDNIIYSQQQGTTFYISTNIDRVAYNHTA
KTSDVEKSSTKKALLNKDFRQSLAFATDRKAGISQVFGDEVAPRKLRTSLTPPTFVQVGEQSFGQVAKAELDKLDGVWKD
VSLDDAQDSLHNVDKAKTKFEAAKKTLQADGVQFPIHLDIPVSSTRPEFVRQAQSYKQSVEEAIGADNVVVDIQQVSDDE
LASMTVLATSNTNTDWDINANSGWGPDYADPSTYLDIFDPTSGPNLLGSLGVVPGKDSSAIKAVGLDKFKELITDANSEK
TNLEKRYAKYAKAQAWLTDSALVIPVHSDGAQMLVTKKVLGTGAGGWVGDKTSENSYKYLKIQDKIVTTKEMDEFRKKFA
DEKAKSNADYQKNLDRHIQD
Nucleotide
Download Length: 1983 bp
>NTDB_id=36323 SMI_RS06605 WP_000747539.1 1295060..1297042(-) (amiA3) [Streptococcus mitis B6]
ATGAAAAAACGTGTTTTCTTAGCAGCAGGAGTTGCTGTACTCTCGGTAGCTGTTCTAGCAGCTTGTTCATCTGGTAATGG
GAATAAGGAAGCAACTAAACCAGTTACTTATACCTATGTATTTTCATCAGATCCTGCGACTCTGGATTATACAGTTTCTG
GGCAAAAGTCTACAAAACAGATTACTGGTAATGTCATTGATGGACTACTGGAAAATGATCAATATGGTAATCTGGTCCCA
TCAGTTGCAGAAGATTGGACTGTTTCAAAAGATGGCTTGACTTATACATATAAAATTCGTAAGGGTATTAAGTGGTATAC
CAATGAAGGCGAAGAATATGGAGAAGTTAAGGCTCAGGATTTTGTGACTGGTCTAAAACACGCTGCTGACAAGAAATCAG
AAGCACTTTATCTTGTACAGGATTCTATTAAAGGATTAGATGACTATGTAAATGGGAAAACAACCGATTTTTCTACTGTT
GGTGTAAAAGCAACAGACGATTATACTGTAGTCTATACTTTAAACCATCCAGAATCTTTCTGGAATTCGAAGACAACAAT
GGGAATTCTTGCTCCTGTTAGCGAAGACTTTTTAGCTTCTAAAGGAGATGACTTTGGTAAGGCGACTGATGTAACAAGCA
TTCTATATAATGGGGCTTATCTTTTAAAAGGTCTTACATCTAAATCTTCTATTGAAATGACTAAAAACCAAAACTATTGG
GATAAACAAAATGTCTTTATTGATGATATTAAGCTGTCTTACTTTGATGGTCAGGATGCAGACTCTCTAGGACGTGGTTT
TGATGAAGGAAATTATCCTGCAGCACCTCTATTTAAAAACTCTGCTAACTATGAACGGCTAAAAGAAAAATATAAAGATA
ACATTATTTATAGTCAACAACAAGGAACTACTTTCTATATTTCGACGAATATTGACCGTGTTGCCTACAATCACACCGCT
AAAACAAGTGATGTAGAAAAATCATCTACTAAGAAGGCTTTGTTGAACAAAGATTTCCGTCAATCCTTGGCTTTTGCTAC
AGATCGTAAAGCAGGAATCTCTCAAGTATTTGGGGACGAAGTAGCACCGCGTAAATTACGTACAAGTTTAACCCCTCCAA
CATTTGTACAGGTAGGAGAGCAGTCATTTGGGCAAGTAGCTAAGGCAGAATTGGATAAATTAGATGGTGTATGGAAAGAT
GTCAGTCTTGATGATGCCCAGGATTCACTTCATAATGTAGATAAGGCTAAGACTAAATTTGAAGCTGCCAAGAAAACTCT
TCAAGCTGATGGAGTACAGTTCCCTATTCATTTAGATATTCCAGTATCTTCTACTCGTCCAGAATTTGTGCGTCAAGCTC
AATCTTATAAACAATCCGTCGAGGAAGCTATTGGAGCAGATAATGTTGTAGTTGATATTCAACAAGTTTCTGACGATGAA
TTGGCAAGTATGACAGTTCTAGCTACTTCTAATACTAATACTGACTGGGATATTAATGCAAATAGTGGATGGGGACCTGA
TTATGCAGATCCGTCAACTTATCTAGATATATTTGATCCAACATCTGGACCAAATCTTCTTGGCTCCTTAGGCGTAGTAC
CAGGTAAAGACAGTTCAGCAATCAAAGCGGTTGGGTTAGATAAGTTTAAAGAGTTAATTACTGATGCTAATAGTGAGAAA
ACAAATCTTGAAAAACGATATGCTAAATATGCAAAAGCTCAAGCTTGGTTAACAGACAGTGCCTTGGTTATTCCTGTACA
CTCAGATGGTGCCCAAATGCTAGTAACGAAGAAAGTTCTAGGTACTGGTGCCGGTGGCTGGGTAGGTGATAAGACCAGTG
AAAATAGCTACAAGTATCTGAAAATTCAAGATAAGATAGTCACTACTAAAGAAATGGATGAGTTCCGCAAGAAATTTGCT
GATGAAAAAGCCAAATCCAATGCTGATTATCAGAAAAACTTAGACCGTCATATTCAAGACTAA
ATGAAAAAACGTGTTTTCTTAGCAGCAGGAGTTGCTGTACTCTCGGTAGCTGTTCTAGCAGCTTGTTCATCTGGTAATGG
GAATAAGGAAGCAACTAAACCAGTTACTTATACCTATGTATTTTCATCAGATCCTGCGACTCTGGATTATACAGTTTCTG
GGCAAAAGTCTACAAAACAGATTACTGGTAATGTCATTGATGGACTACTGGAAAATGATCAATATGGTAATCTGGTCCCA
TCAGTTGCAGAAGATTGGACTGTTTCAAAAGATGGCTTGACTTATACATATAAAATTCGTAAGGGTATTAAGTGGTATAC
CAATGAAGGCGAAGAATATGGAGAAGTTAAGGCTCAGGATTTTGTGACTGGTCTAAAACACGCTGCTGACAAGAAATCAG
AAGCACTTTATCTTGTACAGGATTCTATTAAAGGATTAGATGACTATGTAAATGGGAAAACAACCGATTTTTCTACTGTT
GGTGTAAAAGCAACAGACGATTATACTGTAGTCTATACTTTAAACCATCCAGAATCTTTCTGGAATTCGAAGACAACAAT
GGGAATTCTTGCTCCTGTTAGCGAAGACTTTTTAGCTTCTAAAGGAGATGACTTTGGTAAGGCGACTGATGTAACAAGCA
TTCTATATAATGGGGCTTATCTTTTAAAAGGTCTTACATCTAAATCTTCTATTGAAATGACTAAAAACCAAAACTATTGG
GATAAACAAAATGTCTTTATTGATGATATTAAGCTGTCTTACTTTGATGGTCAGGATGCAGACTCTCTAGGACGTGGTTT
TGATGAAGGAAATTATCCTGCAGCACCTCTATTTAAAAACTCTGCTAACTATGAACGGCTAAAAGAAAAATATAAAGATA
ACATTATTTATAGTCAACAACAAGGAACTACTTTCTATATTTCGACGAATATTGACCGTGTTGCCTACAATCACACCGCT
AAAACAAGTGATGTAGAAAAATCATCTACTAAGAAGGCTTTGTTGAACAAAGATTTCCGTCAATCCTTGGCTTTTGCTAC
AGATCGTAAAGCAGGAATCTCTCAAGTATTTGGGGACGAAGTAGCACCGCGTAAATTACGTACAAGTTTAACCCCTCCAA
CATTTGTACAGGTAGGAGAGCAGTCATTTGGGCAAGTAGCTAAGGCAGAATTGGATAAATTAGATGGTGTATGGAAAGAT
GTCAGTCTTGATGATGCCCAGGATTCACTTCATAATGTAGATAAGGCTAAGACTAAATTTGAAGCTGCCAAGAAAACTCT
TCAAGCTGATGGAGTACAGTTCCCTATTCATTTAGATATTCCAGTATCTTCTACTCGTCCAGAATTTGTGCGTCAAGCTC
AATCTTATAAACAATCCGTCGAGGAAGCTATTGGAGCAGATAATGTTGTAGTTGATATTCAACAAGTTTCTGACGATGAA
TTGGCAAGTATGACAGTTCTAGCTACTTCTAATACTAATACTGACTGGGATATTAATGCAAATAGTGGATGGGGACCTGA
TTATGCAGATCCGTCAACTTATCTAGATATATTTGATCCAACATCTGGACCAAATCTTCTTGGCTCCTTAGGCGTAGTAC
CAGGTAAAGACAGTTCAGCAATCAAAGCGGTTGGGTTAGATAAGTTTAAAGAGTTAATTACTGATGCTAATAGTGAGAAA
ACAAATCTTGAAAAACGATATGCTAAATATGCAAAAGCTCAAGCTTGGTTAACAGACAGTGCCTTGGTTATTCCTGTACA
CTCAGATGGTGCCCAAATGCTAGTAACGAAGAAAGTTCTAGGTACTGGTGCCGGTGGCTGGGTAGGTGATAAGACCAGTG
AAAATAGCTACAAGTATCTGAAAATTCAAGATAAGATAGTCACTACTAAAGAAATGGATGAGTTCCGCAAGAAATTTGCT
GATGAAAAAGCCAAATCCAATGCTGATTATCAGAAAAACTTAGACCGTCATATTCAAGACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiA3 | Streptococcus thermophilus LMD-9 |
54.985 |
100 |
0.552 |
| amiA3 | Streptococcus thermophilus LMG 18311 |
54.532 |
100 |
0.547 |
| amiA | Streptococcus salivarius strain HSISS4 |
54.614 |
100 |
0.547 |