Detailed information NTG0036293

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SMI_RS01480
• Genome accession: NC_013853
• Coordinates: 279506..280516 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090627.1
• Uniprot ID: I0SX71
• Organism: Streptococcus mitis B6
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 274506..285516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMI_RS01455 (smi_0279)	folP	275098..276078 (+)	981	WP_000240961.1	dihydropteroate synthase	-
SMI_RS01460 (smi_0280)	-	276080..277402 (+)	1323	WP_000657452.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
SMI_RS01465 (smi_0281)	folE	277383..277937 (+)	555	WP_000380923.1	GTP cyclohydrolase I FolE	-
SMI_RS01470 (smi_0282)	folK	278095..278907 (+)	813	WP_000372490.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
SMI_RS01475 (smi_0283)	-	278952..279269 (-)	318	WP_000886035.1	DUF960 domain-containing protein	-
SMI_RS01480 (smi_0284)	ccpA	279506..280516 (+)	1011	WP_001090627.1	catabolite control protein A	Regulator
SMI_RS01485 (smi_0285)	-	280570..281532 (-)	963	WP_001124787.1	asparaginase	-
SMI_RS01490 (smi_0286)	-	281598..282989 (+)	1392	WP_000452107.1	Cof-type HAD-IIB family hydrolase	-
SMI_RS10910	-	282986..283108 (+)	123	WP_000693002.1	hypothetical protein	-
SMI_RS01495 (smi_0287)	-	283167..283619 (-)	453	WP_000079151.1	universal stress protein	-
SMI_RS01500 (smi_0288)	-	283780..284082 (+)	303	WP_164925505.1	hypothetical protein	-
SMI_RS01505 (smi_0289)	-	284238..285452 (+)	1215	WP_000666463.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37169.19 Da
• Isoelectric Point: 5.3350

>NTDB_id=36293 SMI_RS01480 WP_001090627.1 279506..280516(+) (ccpA) [Streptococcus mitis B6]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVTYLAKENERIAFVSGPLVDDINGKVRLVGYKEALKKAGISYSEGLVFESKYTYEDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEEFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=36293 SMI_RS01480 WP_001090627.1 279506..280516(+) (ccpA) [Streptococcus mitis B6]
ATGAATACAGACGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCGACAGTTAGCCGTGTAGT
CAATGGCAATAAGAATGTAAAAGAGAATACTCGAAAAAAAGTGCTTGAGGTGATTGACCGTTTGGATTACCGTCCAAATG
CAGTGGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATCCCAAATATTACCAATGGTTATTTCTCA
ACGCTTGCTAAAGGGATTGATGATATCGCTGAAATGTACAAGTACAATATTGTTCTTGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCAGTTGTCAATACACTGTTTTCTAAGCAAGTGGATGGTATCATCTTTATGGGCTACCACTTGACTGAAA
AAATTCGTTCAGAGTTTTCTCGTTCTCGAACACCAGTTGTTCTTGCAGGGACAGTGGATGTAGAACATCAGCTTCCAAGT
GTCAATATTGACTACAAACAAGCAACGATCGATGCAGTAACCTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTAAG
CGGTCCACTAGTGGATGATATCAATGGTAAGGTTCGTTTGGTTGGTTACAAGGAAGCCTTGAAAAAAGCAGGGATTTCTT
ATAGCGAAGGATTGGTATTTGAATCTAAATACACTTATGAAGATGGCTATGCTTTGGCAGAACGCTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCTTGAACGGACTTGCTGATAAGGGTGTGTCTGTGCC
AGAAGAGTTTGAAATCATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACTATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGCATGCGTATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGTTCAACACGAAAACGGAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: I0SX71

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	95.536	100	0.955
ccpA	Streptococcus gordonii str. Challis substr. CH1	89.521	99.405	0.89
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571