Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   FD735_RS05520 Genome accession   NZ_CP040231
Coordinates   1043375..1044733 (-) Length   452 a.a.
NCBI ID   WP_139658685.1    Uniprot ID   A0A5B7Y6W0
Organism   Streptococcus sp. 1643     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1038375..1049733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS05500 (FD735_05500) - 1039490..1041208 (+) 1719 WP_139658683.1 phospho-sugar mutase -
  FD735_RS05505 (FD735_05505) - 1041320..1041667 (+) 348 WP_139658684.1 thioredoxin -
  FD735_RS05510 (FD735_05510) - 1041705..1042478 (-) 774 WP_084943882.1 ion transporter -
  FD735_RS05515 (FD735_05515) vicX 1042573..1043382 (-) 810 WP_084943449.1 MBL fold metallo-hydrolase Regulator
  FD735_RS05520 (FD735_05520) micB 1043375..1044733 (-) 1359 WP_139658685.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FD735_RS05525 (FD735_05525) micA 1044726..1045433 (-) 708 WP_139658686.1 response regulator YycF Regulator
  FD735_RS05530 (FD735_05530) mutY 1045490..1046668 (-) 1179 WP_139658687.1 A/G-specific adenine glycosylase -
  FD735_RS05535 (FD735_05535) pta 1046751..1047725 (-) 975 WP_033629713.1 phosphate acetyltransferase -
  FD735_RS05540 (FD735_05540) - 1047769..1048665 (-) 897 WP_139658688.1 RluA family pseudouridine synthase -
  FD735_RS05545 (FD735_05545) - 1048662..1049480 (-) 819 WP_139658689.1 NAD kinase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51963.30 Da        Isoelectric Point: 4.5520

>NTDB_id=362648 FD735_RS05520 WP_139658685.1 1043375..1044733(-) (micB) [Streptococcus sp. 1643]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIEDQNE

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=362648 FD735_RS05520 WP_139658685.1 1043375..1044733(-) (micB) [Streptococcus sp. 1643]
ATGATTGAAGATATTAGACAAACTATCTTGACCAGCGATTTTATCTTTATCTTGATTTTACTGGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTTGAATTGCTTAAGATAGAAGATGAGTATGAGCTGCGTGATCTAATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTGAATGGGGAATACCTGAGCCTTCGTGTACGTTTTGCTCTGGTTCGTCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAGCAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CGAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCTCTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCAGTTAGATGTGGAATTGATTAATTTTACAGCATTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGCCAGGATGACGAGAAAAAATATGAGCTTGTCAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCTAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGTCGGGCTCAAGGTGGAACCGGTCTAGGT
CTGGCTATCGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACAATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACCAGAATGAGTGA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y6W0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.294

97.124

0.867
  vicK Streptococcus mutans UA159

70.647

88.938

0.628

Multiple sequence alignment