Detailed information NTG0362622

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FD735_RS01145
• Genome accession: NZ_CP040231
• Coordinates: 200199..201209 (+)
• Length: 336 a.a.
• NCBI ID: WP_139658287.1
• Uniprot ID: A0A5B7Y3S1
• Organism: Streptococcus sp. 1643
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 195199..206209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD735_RS01120 (FD735_01120)	-	195431..196753 (+)	1323	WP_139658284.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
FD735_RS01125 (FD735_01125)	folE	196734..197288 (+)	555	WP_000380916.1	GTP cyclohydrolase I FolE	-
FD735_RS01130 (FD735_01130)	folK	197529..198350 (+)	822	WP_139658285.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
FD735_RS01135 (FD735_01135)	-	198343..199626 (+)	1284	WP_139658286.1	DUF308 domain-containing protein	-
FD735_RS01140 (FD735_01140)	-	199677..199994 (-)	318	WP_000886044.1	DUF960 domain-containing protein	-
FD735_RS01145 (FD735_01145)	ccpA	200199..201209 (+)	1011	WP_139658287.1	catabolite control protein A	Regulator
FD735_RS01150 (FD735_01150)	-	201263..202225 (-)	963	WP_001124803.1	asparaginase	-
FD735_RS01155 (FD735_01155)	-	202291..203676 (+)	1386	WP_139658288.1	Cof-type HAD-IIB family hydrolase	-
FD735_RS01160 (FD735_01160)	-	203713..204165 (-)	453	WP_000079161.1	universal stress protein	-
FD735_RS01165 (FD735_01165)	-	204332..204631 (+)	300	WP_139658289.1	hypothetical protein	-
FD735_RS01170 (FD735_01170)	-	204775..205989 (+)	1215	WP_000666454.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37228.26 Da
• Isoelectric Point: 5.5033

>NTDB_id=362622 FD735_RS01145 WP_139658287.1 200199..201209(+) (ccpA) [Streptococcus sp. 1643]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGISVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=362622 FD735_RS01145 WP_139658287.1 200199..201209(+) (ccpA) [Streptococcus sp. 1643]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCCCGTGGTTTAGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCTAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCGAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTCAACACTCTCTTTTCAAAACAAGTTGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTACCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTTAG
TGGACCACTTGTTGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGCGAGGGATTGGTCTTTGAATCAAAATACAGCTATGATGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTCCTAAATGGTTTAGCTGACCATGGTATATCTGTGCC
AGAAGAGTTTGAAATCATTACGACAGATGACTCTCAAATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAATTGGAAGAACGTGAAGTT
CTCCTACCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: A0A5B7Y3S1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.048	100	0.94
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.323	99.405	0.878
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.402	98.512	0.565