Detailed information NTG0361161

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: FCJ76_RS18250
• Genome accession: NZ_CP039935
• Coordinates: 3496994..3498151 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain H19
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3491994..3503151

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FCJ76_RS18220	yvyF	3492251..3492670 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
FCJ76_RS18225	comFC	3492744..3493466 (-)	723	WP_134982986.1	comF operon protein ComFC	Machinery gene
FCJ76_RS18230	comFB	3493430..3493726 (-)	297	WP_015483764.1	late competence protein ComFB	-
FCJ76_RS18235	comFA	3493786..3495173 (-)	1388	Protein_3503	ATP-dependent helicase ComFA	-
FCJ76_RS18240	fakBA	3495279..3496124 (-)	846	WP_137201059.1	DegV family protein	-
FCJ76_RS18245	degU	3496222..3496911 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
FCJ76_RS18250	degS	3496994..3498151 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
FCJ76_RS18255	yvyE	3498368..3499021 (+)	654	WP_003227979.1	YigZ family protein	-
FCJ76_RS18260	tagV	3499021..3500187 (+)	1167	WP_137201061.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
FCJ76_RS18265	tagO	3500260..3501336 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
FCJ76_RS18270	tuaH	3501481..3502674 (-)	1194	WP_080015525.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=361161 FCJ76_RS18250 WP_003227983.1 3496994..3498151(-) (degS) [Bacillus subtilis strain H19]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=361161 FCJ76_RS18250 WP_003227983.1 3496994..3498151(-) (degS) [Bacillus subtilis strain H19]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAAGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCCGATGCTCAGGCAAAACAGGATTTCGGATTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACGATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1