Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GTP13_RS24615 Genome accession   NZ_CP047378
Coordinates   4807079..4807738 (+) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain CAU16175     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 4802079..4812738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GTP13_RS24595 plsC 4802226..4802963 (-) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -
  GTP13_RS24600 parC 4803196..4805454 (-) 2259 WP_001281841.1 DNA topoisomerase IV subunit A -
  GTP13_RS24605 ygiV 4806000..4806482 (-) 483 WP_096317475.1 GyrI-like domain-containing protein -
  GTP13_RS24610 ygiW 4806535..4806927 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  GTP13_RS24615 ciaR 4807079..4807738 (+) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  GTP13_RS24620 qseC 4807735..4809084 (+) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  GTP13_RS24625 ygiZ 4809130..4809462 (-) 333 WP_000912120.1 DUF2645 family protein -
  GTP13_RS24630 mdaB 4809781..4810362 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  GTP13_RS24635 ygiN 4810393..4810707 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  GTP13_RS24640 parE 4810755..4812647 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=359468 GTP13_RS24615 WP_001221502.1 4807079..4807738(+) (ciaR) [Escherichia coli strain CAU16175]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=359468 GTP13_RS24615 WP_001221502.1 4807079..4807738(+) (ciaR) [Escherichia coli strain CAU16175]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment