Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   E8M05_RS11335 Genome accession   NZ_CP039457
Coordinates   1942255..1942476 (-) Length   73 a.a.
NCBI ID   WP_003066558.1    Uniprot ID   E0PG53
Organism   Streptococcus pasteurianus strain WUSP067     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1937255..1947476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS10085 (E8M05_10075) rmuC 1937295..1938569 (-) 1275 WP_136596475.1 DNA recombination protein RmuC -
  E8M05_RS10090 (E8M05_10080) - 1938571..1939200 (-) 630 WP_003066545.1 thiamine diphosphokinase -
  E8M05_RS10095 (E8M05_10085) rpe 1939193..1939855 (-) 663 WP_003066548.1 ribulose-phosphate 3-epimerase -
  E8M05_RS10100 (E8M05_10090) rsgA 1939862..1940734 (-) 873 WP_013852268.1 ribosome small subunit-dependent GTPase A -
  E8M05_RS10115 (E8M05_10105) - 1941180..1941407 (-) 228 WP_003066551.1 hypothetical protein -
  E8M05_RS11660 comD/comD3 1941539..1941853 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  E8M05_RS11335 comE/comE2 1942255..1942476 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  E8M05_RS10125 (E8M05_10115) - 1942448..1942810 (-) 363 WP_061100337.1 bacteriocin immunity protein -
  E8M05_RS10130 (E8M05_10120) - 1942861..1943013 (-) 153 WP_231729917.1 hypothetical protein -
  E8M05_RS10135 (E8M05_10125) - 1943362..1943673 (-) 312 WP_048791097.1 bacteriocin immunity protein -
  E8M05_RS10150 (E8M05_10140) - 1944431..1944568 (+) 138 WP_003066566.1 hypothetical protein -
  E8M05_RS10155 (E8M05_10145) - 1944590..1945897 (-) 1308 WP_003066569.1 sensor histidine kinase -
  E8M05_RS10160 (E8M05_10150) comE/comE1 1945905..1946636 (-) 732 WP_058692509.1 response regulator transcription factor Regulator
  E8M05_RS10165 (E8M05_10155) - 1946653..1946937 (-) 285 WP_231729918.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 73 a.a.        Molecular weight: 8346.75 Da        Isoelectric Point: 9.9655

>NTDB_id=358818 E8M05_RS11335 WP_003066558.1 1942255..1942476(-) (comE/comE2) [Streptococcus pasteurianus strain WUSP067]
MLVTWTGQRNFYGTIREVKNANHKLFQCQKSYLINPDNGVSLDKKEGIVYCVGGKSCYVSKKSMKELKIKLES

Nucleotide


Download         Length: 222 bp        

>NTDB_id=358818 E8M05_RS11335 WP_003066558.1 1942255..1942476(-) (comE/comE2) [Streptococcus pasteurianus strain WUSP067]
ATGTTGGTGACATGGACAGGACAGCGTAATTTTTACGGAACAATCAGAGAAGTTAAAAATGCAAATCATAAGCTATTTCA
ATGCCAAAAATCCTATCTGATTAATCCTGATAATGGCGTCAGTTTGGATAAAAAAGAAGGGATTGTTTATTGTGTAGGTG
GAAAATCTTGTTACGTTTCCAAAAAATCCATGAAAGAATTGAAAATTAAACTAGAAAGTTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(2-71)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PG53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

61.111

98.63

0.603
  comE/comE1 Streptococcus equinus JB1

38.028

97.26

0.37

Multiple sequence alignment