Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   E8M05_RS10160 Genome accession   NZ_CP039457
Coordinates   1945905..1946636 (-) Length   243 a.a.
NCBI ID   WP_058692509.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP067     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1940905..1951636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS10115 (E8M05_10105) - 1941180..1941407 (-) 228 WP_003066551.1 hypothetical protein -
  E8M05_RS11660 comD/comD3 1941539..1941853 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  E8M05_RS11335 comE/comE2 1942255..1942476 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  E8M05_RS10125 (E8M05_10115) - 1942448..1942810 (-) 363 WP_061100337.1 bacteriocin immunity protein -
  E8M05_RS10130 (E8M05_10120) - 1942861..1943013 (-) 153 WP_231729917.1 hypothetical protein -
  E8M05_RS10135 (E8M05_10125) - 1943362..1943673 (-) 312 WP_048791097.1 bacteriocin immunity protein -
  E8M05_RS10150 (E8M05_10140) - 1944431..1944568 (+) 138 WP_003066566.1 hypothetical protein -
  E8M05_RS10155 (E8M05_10145) - 1944590..1945897 (-) 1308 WP_003066569.1 sensor histidine kinase -
  E8M05_RS10160 (E8M05_10150) comE/comE1 1945905..1946636 (-) 732 WP_058692509.1 response regulator transcription factor Regulator
  E8M05_RS10165 (E8M05_10155) - 1946653..1946937 (-) 285 WP_231729918.1 LytTR family DNA-binding domain-containing protein -
  E8M05_RS11665 (E8M05_10160) - 1947180..1947788 (-) 609 WP_136596476.1 hypothetical protein -
  E8M05_RS10175 (E8M05_10165) - 1947960..1948256 (-) 297 WP_003066579.1 bacteriocin immunity protein -
  E8M05_RS10180 (E8M05_10170) - 1948256..1948474 (-) 219 WP_003066580.1 Blp family class II bacteriocin -
  E8M05_RS11900 - 1948666..1948785 (-) 120 WP_253066439.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  E8M05_RS11670 - 1948782..1949102 (-) 321 WP_230321658.1 CPBP family intramembrane glutamic endopeptidase -
  E8M05_RS11675 - 1949159..1949338 (-) 180 WP_003066584.1 hypothetical protein -
  E8M05_RS10190 (E8M05_10180) - 1949508..1949819 (-) 312 WP_003066586.1 hypothetical protein -
  E8M05_RS10195 (E8M05_10185) - 1949908..1950138 (-) 231 WP_061100340.1 bacteriocin -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28430.52 Da        Isoelectric Point: 5.2357

>NTDB_id=358808 E8M05_RS10160 WP_058692509.1 1945905..1946636(-) (comE/comE1) [Streptococcus pasteurianus strain WUSP067]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREQ
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTRNERVEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDKAIRSVYFETGDSCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=358808 E8M05_RS10160 WP_058692509.1 1945905..1946636(-) (comE/comE1) [Streptococcus pasteurianus strain WUSP067]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCCGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCCATTCGTGAACAA
GATGCAACGGCTATCATTGTTTTTGTAACAACCCATTCAGAATTTATGCTGCTGACTTACCAAGCGTTAGTAGGGGCGAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAAAATTCCTTTTTGTTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGACATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGTGTGATTTTGCATACGAGAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGATAAACGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCGATACGAAGTGTTTATTTCGAAACTGGGGACTCTTGCTTAGTTTCGAGGGATAAAATAAAACCTCTATTGAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-238)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

71.193

100

0.712
  comE/blpR Streptococcus mutans UA159

48.954

98.354

0.481
  comE/comE2 Streptococcus equinus JB1

45.868

99.588

0.457

Multiple sequence alignment