Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   E8M05_RS07820 Genome accession   NZ_CP039457
Coordinates   1503115..1503825 (-) Length   236 a.a.
NCBI ID   WP_003065770.1    Uniprot ID   A0AAW6YI35
Organism   Streptococcus pasteurianus strain WUSP067     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1498115..1508825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS07805 (E8M05_07795) rnc 1500020..1500706 (-) 687 WP_003065764.1 ribonuclease III -
  E8M05_RS07810 (E8M05_07800) vicX 1500960..1501769 (-) 810 WP_003065766.1 MBL fold metallo-hydrolase Regulator
  E8M05_RS07815 (E8M05_07805) vicK 1501770..1503122 (-) 1353 WP_003065768.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E8M05_RS07820 (E8M05_07810) vicR 1503115..1503825 (-) 711 WP_003065770.1 response regulator YycF Regulator
  E8M05_RS07825 (E8M05_07815) - 1504130..1504894 (+) 765 WP_003065772.1 amino acid ABC transporter ATP-binding protein -
  E8M05_RS07830 (E8M05_07820) - 1504905..1505717 (+) 813 WP_013852112.1 transporter substrate-binding domain-containing protein -
  E8M05_RS07835 (E8M05_07825) - 1505734..1506438 (+) 705 WP_003065775.1 amino acid ABC transporter permease -
  E8M05_RS07840 (E8M05_07830) - 1506450..1507097 (+) 648 WP_003065777.1 amino acid ABC transporter permease -
  E8M05_RS07845 (E8M05_07835) - 1507189..1507797 (-) 609 WP_003065779.1 TVP38/TMEM64 family protein -
  E8M05_RS07850 (E8M05_07840) - 1508045..1508347 (-) 303 WP_003065782.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27119.93 Da        Isoelectric Point: 4.7040

>NTDB_id=358801 E8M05_RS07820 WP_003065770.1 1503115..1503825(-) (vicR) [Streptococcus pasteurianus strain WUSP067]
MKKILIVDDEKPISDIIKFNLAKEGYETVTAFDGREAITKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASASNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=358801 E8M05_RS07820 WP_003065770.1 1503115..1503825(-) (vicR) [Streptococcus pasteurianus strain WUSP067]
ATGAAAAAAATTCTTATCGTGGATGATGAAAAACCAATTTCGGATATTATTAAATTTAATTTAGCTAAAGAAGGTTATGA
AACTGTAACGGCTTTTGATGGTCGTGAAGCTATTACAAAGTTTGAGGAAGAAAATCCAGATTTAATTATCCTGGATTTGA
TGTTGCCAGAGTTGGATGGGCTTGAAGTGGCTAAGGAAGTTCGCAAGACAAGTCATATTCCAATCATCATGTTGTCTGCT
AAGGATAGCGAGTTTGATAAAGTTATCGGTCTTGAAATTGGTGCAGATGACTATGTAACCAAACCATTTTCAAATCGTGA
ATTGTTGGCGCGTGTTAAAGCGCACCTTCGTCGTACAGAAAATATTGAAACAGCAGTTGCTGAAGAAAATGCTTCGGCTT
CAAATTCAGAAATCACAATTGGCGACTTAAAAATTTTACCAGATGCCTTTGTAGCACAAAAACGTGGTGAAGATATCGAA
TTAACACACCGTGAGTTTGAATTGCTTCATCATTTGGCAACTCATATGGGACAAGTCATGACTCGTGAATATCTTTTGGA
AACCGTTTGGGGCTATGATTATTTTGGTGATGTGCGTACGGTTGATGTAACGATTCGTCGTTTACGCGAAAAAATTGAAG
ATACACCAAGCCGTCCAGAATATATTTTGACACGTCGGGGTGTTGGGTACTACATGAAGTCATATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

77.35

99.153

0.767
  covR Streptococcus salivarius strain HSISS4

47.414

98.305

0.466
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

37.288

100

0.373

Multiple sequence alignment