Detailed information NTG0358188

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: EA665_RS04450
• Genome accession: NZ_CP039343
• Coordinates: 931052..933484 (+)
• Length: 810 a.a.
• NCBI ID: WP_024432326.1
• Uniprot ID: A0A1S2FTA2
• Organism: Acinetobacter baumannii strain TG31302
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	926022..938161	931052..933484	within	0

Gene organization within MGE regions

Location: 926022..938161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EA665_RS19850	-	926022..926168 (-)	147	WP_000691794.1	hypothetical protein	-
EA665_RS04425 (EA665_004425)	-	926202..927143 (-)	942	WP_000795878.1	hypothetical protein	-
EA665_RS04430 (EA665_004430)	-	927400..927885 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
EA665_RS04435 (EA665_004435)	-	927896..928804 (+)	909	WP_001140072.1	DMT family transporter	-
EA665_RS20215	-	928834..928914 (-)	81	Protein_835	PilZ domain-containing protein	-
EA665_RS04440 (EA665_004440)	-	929052..930287 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
EA665_RS04445 (EA665_004445)	lolD	930280..930966 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
EA665_RS04450 (EA665_004450)	comA/comEC	931052..933484 (+)	2433	WP_024432326.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EA665_RS04455 (EA665_004455)	-	933437..934420 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
EA665_RS04460 (EA665_004460)	sppA	934557..935573 (+)	1017	WP_001286615.1	signal peptide peptidase SppA	-
EA665_RS04465 (EA665_004465)	-	935592..936401 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
EA665_RS04470 (EA665_004470)	purN	936465..937094 (-)	630	WP_000975531.1	phosphoribosylglycinamide formyltransferase	-
EA665_RS04475 (EA665_004475)	purM	937091..938161 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92306.59 Da
• Isoelectric Point: 8.5829

>NTDB_id=358188 EA665_RS04450 WP_024432326.1 931052..933484(+) (comA/comEC) [Acinetobacter baumannii strain TG31302]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINHLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSSSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSTLIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLGSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIIAACAWFVVKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVMMNKTSQQIQLNILDVGQGQ
AIFLQHPQQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPIIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYSELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTLEQGTLSFVLENHKLVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=358188 EA665_RS04450 WP_024432326.1 931052..933484(+) (comA/comEC) [Acinetobacter baumannii strain TG31302]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCATTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCATTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGCCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAACGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAGTAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTTTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAACCCTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTA
AGTCTGGGCTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATAGCTGCTTGCGCATGGTTTGTAGTAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATAATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGAATAT
TATGTTGTTTACCCCTAGTTATGATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGCCAGGGGCAG
GCTATTTTTCTACAACATCCCCAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTATTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATTCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAATCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTAGTGCTAGGGCATCATGGAAGTAAGCATAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTGCATA
TTCCGCTAAAAAGTACTTTGGAACAAGGGACCTTAAGTTTTGTGCTGGAAAACCACAAATTAGTTTTACATGACCGACGT
TTGGATCGGCTCTGGCTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Competence protein (Competence) (243-521)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-638)

3D structure

• AlphaFold DB: A0A1S2FTA2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii strain A118	98.765	100	0.988
comA/comEC	Acinetobacter baumannii D1279779	97.654	100	0.977
comA/comEC	Acinetobacter baylyi ADP1	50.062	100	0.501