Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   E6A55_RS05930 Genome accession   NZ_CP039287
Coordinates   1276293..1278707 (+) Length   804 a.a.
NCBI ID   WP_011614916.1    Uniprot ID   Q0KCF4
Organism   Cupriavidus necator H16     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1271293..1283707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E6A55_RS05910 (E6A55_05910) - 1272036..1273145 (-) 1110 WP_011614914.1 hypothetical protein -
  E6A55_RS05915 (E6A55_05915) - 1273282..1274532 (+) 1251 WP_010809011.1 lipoprotein-releasing ABC transporter permease subunit -
  E6A55_RS05920 (E6A55_05920) lolD 1274525..1275265 (+) 741 WP_011614915.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  E6A55_RS05925 (E6A55_05925) - 1275278..1276117 (+) 840 WP_010809009.1 TatD family hydrolase -
  E6A55_RS05930 (E6A55_05930) comA 1276293..1278707 (+) 2415 WP_011614916.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  E6A55_RS05935 (E6A55_05935) - 1278710..1279657 (-) 948 WP_011614917.1 MurR/RpiR family transcriptional regulator -
  E6A55_RS05940 (E6A55_05940) - 1279701..1279913 (-) 213 WP_136227752.1 hypothetical protein -
  E6A55_RS05945 (E6A55_05945) edd 1279912..1281807 (+) 1896 WP_011614918.1 phosphogluconate dehydratase -
  E6A55_RS05950 (E6A55_05950) - 1281958..1282464 (+) 507 WP_037024362.1 gluconokinase -

Sequence

Protein


Download         Length: 804 a.a.        Molecular weight: 84948.93 Da        Isoelectric Point: 11.2576

>NTDB_id=357878 E6A55_RS05930 WP_011614916.1 1276293..1278707(+) (comA) [Cupriavidus necator H16]
MRWFVVAFVAGCWTLQQQSMLPPQDGLRLGAVALTLVALGIALWGRRLHVVLHGLALAGLAFGAAFCWAAWRAELRMRDW
LPATLEARDLDVRGVVSGLPADAATGTRFALTVEQGDAGQPLPRRVILNWRGAPPDLRPGQRLTLTLRLRRPRGLANPFG
SDYAYWLLAQGYGATGYVRRAQGPPQDASAERLAWRIEAVRAAVRDHLRAALPADARFGAVLTALVIGDQRGIDADDWQL
FRRTGVSHLVAISGLHITMIAGMAASLAGLLWRHSFGLGRWLRRPLPLWLPARQAALVAAVASALAYGLLAGMQVPALRT
VAMLCVAAIAVWSARAPPASVVLAWAALAALLLDPWAVMLPGFWLSFGAVAVIFFAARPGRDASTEGRWQRLRSVLAAGA
RTQWAVTIGLVPLTLLLFGQVSVVSPLANAVAIPVVSLLVTPLALLGAALPMALAGPVLAVAHLAMVALAAVLGWLSALP
WAMWEAASAGPLALVLAALGVGLLVAPVATARARLHGGLLMLPMLLARGPPVAHGEFRAVMLDVGQGTAVLVRTRAHALL
YDTGPSYASGSSAGAQVVVPLLRGEGVGRIDHLMVSHEDTDHAGGVADITAAVAVSARSTGAPAGHVLLGSAANDWSPCA
AGQQWEWDGVRFTVLHPLAEQAQQAAIASNARSCVLRVDAAAHSLLLTGDIGVAQERALIDRLPAEVLRADVLVVAHHGS
GTSSGAAWLEAVRPSAAVFQLGYANRYRHPSGEVWERYGRAGVLRYRTDETGAVTMDTAPGGFALSVFRQAQPRYWRARP
PAPR

Nucleotide


Download         Length: 2415 bp        

>NTDB_id=357878 E6A55_RS05930 WP_011614916.1 1276293..1278707(+) (comA) [Cupriavidus necator H16]
GTGCGCTGGTTCGTGGTGGCTTTCGTCGCGGGATGCTGGACGCTGCAGCAGCAGTCAATGCTGCCGCCGCAGGATGGCCT
GCGCCTCGGTGCTGTGGCGCTGACATTGGTCGCTCTCGGCATCGCCTTGTGGGGCAGGCGCCTGCACGTCGTGCTGCATG
GCCTGGCGCTTGCCGGGCTGGCGTTCGGCGCCGCCTTCTGCTGGGCGGCCTGGCGGGCCGAACTGCGCATGCGCGACTGG
CTGCCGGCCACGCTGGAGGCGCGCGACCTCGACGTGCGCGGCGTGGTGTCGGGGCTGCCGGCGGATGCCGCCACCGGGAC
GCGTTTTGCCTTGACTGTGGAGCAGGGTGATGCGGGCCAGCCTCTGCCGCGCCGCGTGATCCTCAACTGGCGTGGCGCAC
CGCCCGACCTGCGTCCCGGGCAGCGCCTCACGCTGACCCTGCGCCTGCGGCGTCCGCGCGGACTCGCCAATCCTTTTGGT
TCTGACTACGCCTATTGGCTGCTGGCGCAGGGCTATGGCGCCACCGGCTATGTGCGCCGCGCACAAGGGCCGCCGCAGGA
CGCGTCCGCGGAGCGGCTGGCATGGCGCATTGAGGCCGTGCGCGCCGCCGTGCGCGATCACCTGCGCGCGGCGCTGCCGG
CCGATGCGCGCTTTGGCGCGGTGCTGACCGCGCTGGTCATTGGCGACCAGCGCGGTATCGATGCGGACGACTGGCAACTG
TTCCGGCGCACCGGCGTCAGCCACCTGGTCGCGATCTCCGGGCTGCATATCACCATGATCGCCGGCATGGCGGCGTCGCT
TGCCGGGCTGTTGTGGCGGCATTCGTTCGGACTCGGCCGCTGGCTGCGCCGGCCGTTGCCGCTGTGGCTGCCGGCCCGGC
AGGCCGCGCTGGTGGCGGCCGTGGCCAGTGCGCTGGCTTACGGCCTGCTGGCCGGCATGCAGGTCCCGGCGCTGCGCACC
GTGGCCATGCTCTGCGTGGCGGCCATTGCGGTATGGAGTGCGCGTGCGCCGCCCGCCTCGGTGGTGCTGGCGTGGGCGGC
GCTGGCGGCATTGCTGCTGGATCCGTGGGCGGTGATGTTGCCCGGCTTCTGGCTGTCCTTCGGCGCGGTGGCCGTGATCT
TCTTCGCGGCCCGGCCCGGCCGGGATGCTTCGACGGAAGGGCGTTGGCAACGCCTGCGGTCCGTGCTCGCCGCCGGGGCG
CGCACGCAGTGGGCCGTGACCATCGGGCTGGTGCCGCTGACGTTGCTGCTGTTCGGCCAGGTATCGGTGGTGTCGCCGTT
GGCCAATGCGGTGGCGATCCCGGTCGTCAGCCTGCTGGTGACGCCGCTGGCTTTGCTCGGCGCCGCCTTGCCGATGGCGC
TGGCCGGGCCGGTGCTGGCGGTGGCCCACCTGGCTATGGTGGCGCTGGCCGCGGTGCTGGGCTGGCTTTCGGCGCTGCCA
TGGGCGATGTGGGAAGCGGCCAGCGCGGGGCCGTTGGCGCTGGTGCTGGCGGCGCTCGGTGTCGGGCTGCTGGTCGCGCC
GGTCGCCACCGCGCGCGCGCGCCTGCACGGCGGGCTGCTGATGTTGCCGATGCTGCTGGCGCGCGGCCCGCCGGTTGCGC
ATGGCGAGTTCCGCGCGGTGATGCTGGACGTGGGGCAGGGCACGGCGGTGCTGGTGCGAACGCGCGCCCATGCGCTGCTG
TATGACACCGGGCCGTCTTATGCGTCGGGATCCAGCGCCGGTGCGCAGGTGGTGGTGCCATTGCTGCGGGGCGAGGGGGT
TGGCCGGATCGACCACCTGATGGTCAGCCATGAAGACACCGACCATGCCGGCGGCGTGGCGGACATCACGGCGGCGGTGG
CCGTGTCCGCGCGCAGCACCGGAGCGCCTGCCGGTCACGTTCTGCTTGGGTCGGCGGCCAATGACTGGTCGCCATGCGCG
GCGGGCCAGCAATGGGAGTGGGACGGCGTGCGCTTTACCGTGCTGCATCCGCTCGCGGAGCAGGCGCAGCAGGCAGCCAT
TGCCAGCAATGCGCGCAGCTGCGTGCTGCGCGTGGATGCGGCGGCGCACAGCCTGCTGCTGACCGGAGACATCGGCGTGG
CGCAGGAGCGTGCGTTGATCGACAGGTTGCCGGCCGAGGTGCTGCGTGCCGACGTGCTGGTGGTGGCCCACCATGGCAGC
GGCACCTCATCCGGTGCAGCCTGGCTGGAGGCAGTGCGCCCGTCGGCGGCGGTGTTCCAGCTGGGTTATGCCAACCGCTA
TCGCCACCCGAGCGGCGAGGTGTGGGAGCGCTACGGCCGCGCGGGCGTCCTGCGCTACCGGACCGATGAAACCGGCGCGG
TGACCATGGACACTGCGCCCGGGGGCTTTGCGTTGTCGGTGTTCCGGCAGGCGCAGCCGCGCTACTGGCGGGCGCGACCG
CCGGCGCCGCGTTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(29-181)

Metallo-beta-lactamase superfamily (Lactamase_B)

(543-738)

Competence protein (Competence)

(225-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q0KCF4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

48.507

100

0.505
  comA Pseudomonas stutzeri DSM 10701

39.153

94.03

0.368

Multiple sequence alignment