Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GR131_RS16600 Genome accession   NZ_CP047147
Coordinates   3866743..3867402 (-) Length   219 a.a.
NCBI ID   WP_159312755.1    Uniprot ID   -
Organism   Streptomyces sp. GF20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3861743..3872402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GR131_RS16570 (GR131_16570) - 3861793..3861990 (-) 198 WP_159312753.1 hypothetical protein -
  GR131_RS16575 (GR131_16575) - 3861987..3862427 (-) 441 WP_159313929.1 ATP-binding protein -
  GR131_RS16580 (GR131_16580) - 3862772..3864049 (+) 1278 WP_201305760.1 XRE family transcriptional regulator -
  GR131_RS16585 (GR131_16585) - 3864126..3864566 (+) 441 Protein_3285 GNAT family N-acetyltransferase -
  GR131_RS16590 (GR131_16590) - 3864617..3865158 (+) 542 Protein_3286 flavoprotein -
  GR131_RS16595 (GR131_16595) - 3865280..3865858 (-) 579 WP_159312754.1 DUF4352 domain-containing protein -
  GR131_RS16600 (GR131_16600) vraR 3866743..3867402 (-) 660 WP_159312755.1 response regulator transcription factor Regulator
  GR131_RS16605 (GR131_16605) - 3867411..3868694 (-) 1284 WP_159312756.1 sensor histidine kinase -
  GR131_RS16610 (GR131_16610) - 3869082..3869657 (+) 576 WP_031178660.1 heme-binding protein -
  GR131_RS16615 (GR131_16615) - 3869698..3870318 (+) 621 WP_018893691.1 ankyrin repeat domain-containing protein -
  GR131_RS16620 (GR131_16620) - 3870360..3870767 (-) 408 WP_003949595.1 RidA family protein -
  GR131_RS16625 (GR131_16625) - 3870939..3871319 (+) 381 WP_003949596.1 helix-turn-helix domain-containing protein -
  GR131_RS16630 (GR131_16630) - 3871323..3872015 (-) 693 WP_049979125.1 hypothetical protein -
  GR131_RS32720 - 3872173..3872277 (-) 105 WP_234479791.1 DUF397 domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23545.02 Da        Isoelectric Point: 6.3864

>NTDB_id=357754 GR131_RS16600 WP_159312755.1 3866743..3867402(-) (vraR) [Streptomyces sp. GF20]
MPAADVEPPTPAPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGEEALALTTLHHPDLVLMDLQLGEGIDGVETTR
RLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTP
RERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRAGAVAVGKERRLLG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=357754 GR131_RS16600 WP_159312755.1 3866743..3867402(-) (vraR) [Streptomyces sp. GF20]
GTGCCCGCCGCCGACGTCGAGCCCCCCACCCCTGCCCCCGTCCGCCTCCTCCTCTGCGACGACCACGCCGTGGTCCGCGC
CGGCCTGCGCGCCCTCCTCTCCAGCGCCCCCGGCATCGAGGTCGTGGCCGAAGCAGGCAGCGGCGAGGAAGCCCTCGCCC
TGACCACCCTCCACCACCCCGACCTGGTCCTCATGGACCTCCAACTAGGCGAAGGAATCGACGGAGTCGAAACCACCCGC
CGCCTCACCACCCTCCCCGACCACCCCCCGTACGTCCTCGTCCTCACCACCTACGACACCGACGCCGACATCACCCGAGC
CGTCGAAGCCGGCGCCACGGGCTACCTCCTGAAAGCCGAACGCCCCGAAGAACTCTTCACCGCCATCAGGGCTGCGGCCT
CGGGGCGTACGGCGTTGTCCCCGCCTGTGGCGCAGAGGGTGATGACTCACTTGCGGAACCCGCAGCCGGAGTTGACGCCT
AGGGAGCGGGATATTTTGCGGCACTTGACGCAGGGGCTGGGGAACCGGGAGATCGCCCGGGCGTTGTTTATCAGCGAGGC
GACGGTGAAGACCCATTTGGGGCGGATTTATCAGAAGTTGGGGGTGGAGACTCGGGCGGGGGCGGTGGCTGTGGGGAAGG
AGCGGCGGTTGTTGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-210)

Response regulator receiver domain (Response_reg)

(17-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.559

97.26

0.365
  letA Legionella pneumophila str. Paris

37.441

96.347

0.361
  letA Legionella pneumophila strain ERS1305867

37.441

96.347

0.361

Multiple sequence alignment