Detailed information NTG0357555

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GLX30_RS23445
• Genome accession: NZ_CP047140
• Coordinates: 5286812..5288101 (+)
• Length: 429 a.a.
• NCBI ID: WP_005317626.1
• Uniprot ID: B5HDG3
• Organism: Streptomyces sp. Tu 2975
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5281812..5293101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLX30_RS23415 (GLX30_23535)	-	5282783..5282977 (+)	195	WP_159692042.1	hypothetical protein	-
GLX30_RS23430 (GLX30_23550)	tig	5283583..5284979 (+)	1397	Protein_4688	trigger factor	-
GLX30_RS23435 (GLX30_23555)	-	5285306..5285911 (+)	606	WP_159695205.1	ATP-dependent Clp protease proteolytic subunit	-
GLX30_RS23440 (GLX30_23560)	clpP	5285954..5286664 (+)	711	WP_159692045.1	ATP-dependent Clp protease proteolytic subunit	Regulator
GLX30_RS23445 (GLX30_23565)	clpX	5286812..5288101 (+)	1290	WP_005317626.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
GLX30_RS23450 (GLX30_23570)	-	5288174..5289148 (-)	975	WP_159692047.1	hypothetical protein	-
GLX30_RS23455 (GLX30_23575)	-	5289285..5291906 (+)	2622	WP_159692049.1	valine--tRNA ligase	-

Sequence

Protein

• Length: 429 a.a.
• Molecular weight: 46957.84 Da
• Isoelectric Point: 4.8795

>NTDB_id=357555 GLX30_RS23445 WP_005317626.1 5286812..5288101(+) (clpX) [Streptomyces sp. Tu 2975]
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEP
AKKALSVAVYNHYKRVQAGENGGAQGRDDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGED
VENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQ
IDTTNVLFIVGGAFAGLEKIIESRAGAKGIGFGATIRSKREIEASDQFQEVMPEDLVKFGMIPEFIGRLPVITSVHNLDR
EALLKILVEPRNALVKQYQRLFELDGVELDFDLPALEAIADQAILRGTGARGLRAIMEEVLQSVMYEVPSRKDVARVVIT
RDVVRNNVNPTLVPRIVKDDGNGRHEKSA

Nucleotide

• Length: 1290 bp

>NTDB_id=357555 GLX30_RS23445 WP_005317626.1 5286812..5288101(+) (clpX) [Streptomyces sp. Tu 2975]
GTGGCACGCATCGGTGATGGCGGCGACCTGCTCAAGTGCTCGTTCTGCGGAAAGAGCCAGAAGCAGGTGAAGAAGCTCAT
CGCAGGCCCCGGTGTGTACATCTGCGACGAGTGCATCGACCTCTGCAACGAGATCATCGAGGAGGAGCTCGCAGAGACCT
CCGAGGTGCGGTGGGAGGAACTTCCCAAACCGCGCGAGATCTATGAGTTCCTCGAGGGGTACGTCGTCGGGCAGGAGCCC
GCGAAGAAGGCCCTCTCGGTCGCGGTGTACAACCACTACAAGCGCGTCCAGGCCGGCGAGAACGGCGGTGCGCAGGGCCG
GGACGACGCGATCGAGCTCGCCAAGTCCAACATCCTGCTGCTGGGTCCCACGGGCTCCGGCAAGACGCTGCTCGCCCAGA
CGCTCGCCCGCATGCTCAACGTCCCGTTCGCCATCGCCGACGCGACCGCGCTGACGGAGGCGGGCTATGTCGGCGAGGAC
GTGGAGAACATCCTGCTCAAGCTGATCCAGGCGGCCGACTACGACGTCAAGAAGGCCGAGACCGGGATCATCTACATCGA
CGAGATCGACAAGGTCGCCCGAAAGAGCGAAAACCCGTCGATCACGCGGGACGTCTCCGGCGAGGGCGTCCAGCAGGCCC
TGCTCAAGATCCTGGAAGGCACCACGGCCTCCGTACCCCCGCAGGGCGGCCGCAAGCACCCGCACCAGGAGTTCATCCAG
ATCGACACGACGAACGTGCTCTTCATCGTGGGCGGCGCGTTCGCCGGCCTCGAGAAGATCATCGAGTCGCGCGCGGGAGC
GAAGGGCATCGGCTTCGGCGCGACGATCCGCTCCAAGCGCGAGATCGAGGCGAGCGACCAGTTCCAGGAGGTCATGCCGG
AGGACCTGGTCAAGTTCGGCATGATCCCCGAGTTCATCGGCCGTCTGCCCGTCATCACCTCGGTCCACAACCTGGACCGC
GAGGCGCTGCTGAAGATTCTCGTCGAGCCGCGCAACGCGCTGGTCAAGCAGTACCAGCGCCTCTTCGAACTCGACGGCGT
CGAGCTGGACTTCGACCTCCCCGCCCTCGAGGCCATCGCCGACCAGGCGATCCTCCGCGGCACCGGCGCGCGCGGCCTGC
GCGCCATCATGGAGGAGGTCCTCCAGTCGGTGATGTACGAGGTTCCGTCCCGCAAGGACGTGGCGCGCGTCGTCATCACG
CGTGACGTCGTCCGCAACAACGTCAACCCGACGCTGGTCCCGCGCATCGTCAAGGACGACGGCAACGGCCGTCACGAGAA
GAGCGCGTAG

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (115-312)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (318-396)

3D structure

• AlphaFold DB: B5HDG3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	63.682	93.706	0.597
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.771	95.804	0.515