Detailed information NTG0357535

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: GLX30_RS16110
• Genome accession: NZ_CP047140
• Coordinates: 3668435..3669559 (+)
• Length: 374 a.a.
• NCBI ID: WP_005314096.1
• Uniprot ID: B5HI61
• Organism: Streptomyces sp. Tu 2975
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3663435..3674559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLX30_RS16095 (GLX30_16180)	-	3664166..3664972 (+)	807	WP_159688995.1	hypothetical protein	-
GLX30_RS16100 (GLX30_16185)	-	3665081..3666775 (-)	1695	WP_159688997.1	hypothetical protein	-
GLX30_RS16105 (GLX30_16190)	radA/sms	3666948..3668390 (+)	1443	WP_159689000.1	DNA repair protein RadA	Machinery gene
GLX30_RS16110 (GLX30_16195)	disA	3668435..3669559 (+)	1125	WP_005314096.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
GLX30_RS16115 (GLX30_16200)	-	3669640..3670491 (-)	852	WP_159689003.1	hypothetical protein	-
GLX30_RS16120 (GLX30_16205)	-	3670667..3671320 (+)	654	WP_159689006.1	phosphatase PAP2 family protein	-
GLX30_RS16125 (GLX30_16210)	-	3671540..3672454 (+)	915	WP_159689009.1	A/G-specific adenine glycosylase	-
GLX30_RS16130 (GLX30_16215)	-	3672656..3673228 (+)	573	WP_159689012.1	SigE family RNA polymerase sigma factor	-
GLX30_RS16135 (GLX30_16220)	-	3673216..3673881 (+)	666	WP_208545427.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40106.88 Da
• Isoelectric Point: 4.9483

>NTDB_id=357535 GLX30_RS16110 WP_005314096.1 3668435..3669559(+) (disA) [Streptomyces sp. Tu 2975]
MAAKDGASAPGKSGGGSGNEALIRAALSAVAPGTALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDISKIHRAGVQLVPDASIPTEETGTRHRTADRVSRQCGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVEEALAELDALSHGELLELPTVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=357535 GLX30_RS16110 WP_005314096.1 3668435..3669559(+) (disA) [Streptomyces sp. Tu 2975]
GTGGCAGCCAAGGACGGGGCATCAGCACCCGGAAAGTCCGGCGGAGGCTCCGGCAACGAAGCGCTGATCCGCGCCGCCCT
GAGCGCCGTCGCACCGGGCACCGCCCTGCGTGACGGACTGGAGCGCATCCTCCGGGGCAACACCGGAGGCCTGATCGTTC
TCGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGTTTCGTGCTGGACGTGGAATTCACCGCCACCAGGTTGCGC
GAGCTGTGCAAGCTGGACGGCGCGCTCATCCTCGACAAGGACATCTCCAAGATCCACCGGGCCGGCGTGCAGCTGGTCCC
CGACGCCTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACCGCGGACCGGGTCTCACGTCAGTGCGGCTTCCCGG
TGGTGTCCGTGTCGCAGTCGATGCGCCTGATCGCGCTGTACGTGGACGGAGAGCGCCGGGTCCTCGAGGAGTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCGCTGGCCACGCTCGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACACTGTC
GGCCCTCGAGATCGAGGACCTGGTCACCGTCCGCGACGTCACCGCTGTCGCACAGCGTCTGGAGATGGTGCGCCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGCCGTCTGCTGGCCCTGCAGCTCGACGAGTTGATCGCG
GGTGTCGAGCCGGAGCGCGAACTGGTCGTGCGCGACTACGTACCGGAGCCGACGGCGAAGCGCTCGCGCACCGTGGAGGA
GGCACTCGCGGAGCTGGACGCGCTCAGCCACGGTGAACTCCTCGAACTGCCCACCGTGGCAAGGGCGCTCGGCTACAGCG
GTTCGCCGGAGACGCTCGACTCGGCTGTCTCGCCGCGCGGTTACCGGCTGCTGGCGAAGGTTCCGCGGCTGCCGGGCGCG
ATCATCGAGCGGCTCGTCGAGCACTTCGGCGGTCTCCAGAAGCTGCTCGCGGCCAGCGTGGACGACCTTCAGGCGGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGGGAGGGCCTGTCGCGGCTCGCGGAGTCCTCGATCCTCGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

3D structure

• AlphaFold DB: B5HI61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.429	96.524	0.438