Detailed information NTG0356813

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: E5A72_RS19920
• Genome accession: NZ_CP039025
• Coordinates: 1885078..1885938 (-)
• Length: 286 a.a.
• NCBI ID: WP_001152268.1
• Uniprot ID: A0A1E3M8A8
• Organism: Acinetobacter baumannii ATCC 17978 substr. PMR-High
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1880078..1890938

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E5A72_RS09245 (E5A72_09245)	-	1880966..1882276 (+)	1311	WP_000753297.1	tetratricopeptide repeat protein	-
E5A72_RS09250 (E5A72_09250)	-	1882353..1882679 (+)	327	WP_000099685.1	pyrimidine/purine nucleoside phosphorylase	-
E5A72_RS09255 (E5A72_09255)	rlmB	1882781..1883530 (+)	750	WP_001118149.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
E5A72_RS09260 (E5A72_09260)	-	1883566..1884483 (+)	918	WP_000075016.1	DMT family transporter	-
E5A72_RS09265 (E5A72_09265)	coaE	1884480..1885076 (-)	597	WP_000874127.1	dephospho-CoA kinase	-
E5A72_RS19920 (E5A72_09270)	pilD	1885078..1885938 (-)	861	WP_001152268.1	prepilin peptidase	Machinery gene
E5A72_RS09275 (E5A72_09275)	pilC	1885938..1887164 (-)	1227	WP_000279216.1	type II secretion system F family protein	Machinery gene
E5A72_RS09280 (E5A72_09280)	pilB	1887194..1888906 (-)	1713	WP_001274983.1	type IV-A pilus assembly ATPase PilB	Machinery gene
E5A72_RS09285 (E5A72_09285)	tpiA	1889197..1889991 (+)	795	WP_000016939.1	triose-phosphate isomerase	-
E5A72_RS09290 (E5A72_09290)	secG	1890004..1890333 (+)	330	WP_000555570.1	preprotein translocase subunit SecG	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 32094.47 Da
• Isoelectric Point: 7.1041

>NTDB_id=356813 E5A72_RS19920 WP_001152268.1 1885078..1885938(-) (pilD) [Acinetobacter baumannii ATCC 17978 substr. PMR-High]
MQDIIAYFIQNFTALYIAVALVSLCIGSFLNVVIYRTPKMMEQDWQQECQMLLNPEQPIIDHEKLTLSKPASSCPACQQP
IRWYQNIPVISWLVLRGKCGHCQHPISIRYPAIELLTMLCSLVVVMVFGPTIQMLFGLVLTWVLIALTFIDFDTQLLPDR
FTLTLAALGLGINTFNIYTSPNSAIWGYLIGFLCLWIVYYLFKVITGKEGMGYGDFKLLAALGAWMGPLMLPLIVLLSSL
LGAIIGIILLKLRNDNQPFAFGPYIAIAGWVAFLWGDQIMKIYLGG

Nucleotide

• Length: 861 bp

>NTDB_id=356813 E5A72_RS19920 WP_001152268.1 1885078..1885938(-) (pilD) [Acinetobacter baumannii ATCC 17978 substr. PMR-High]
ATGCAAGACATCATTGCGTATTTTATTCAAAACTTTACTGCACTTTATATTGCTGTTGCACTCGTGAGCCTATGTATCGG
TAGCTTTCTTAATGTAGTGATTTACCGCACGCCAAAAATGATGGAGCAAGATTGGCAGCAAGAATGCCAAATGCTGCTCA
ATCCTGAGCAACCCATTATTGATCATGAGAAGTTAACTTTAAGTAAGCCTGCTTCATCGTGCCCTGCATGTCAGCAACCG
ATCCGTTGGTATCAAAATATTCCTGTTATAAGCTGGCTTGTGTTAAGAGGAAAATGTGGTCATTGCCAGCACCCGATTAG
TATTCGCTATCCAGCCATCGAACTACTCACCATGCTATGTTCATTAGTAGTAGTCATGGTATTTGGCCCAACCATACAAA
TGCTTTTTGGACTCGTCCTCACATGGGTACTGATAGCCCTTACCTTTATTGATTTCGATACACAATTATTGCCTGATCGC
TTTACCCTAACTTTAGCTGCGCTCGGCTTAGGTATTAATACCTTTAATATTTATACCTCACCCAACTCAGCCATTTGGGG
TTATCTCATTGGTTTCCTATGTCTTTGGATTGTCTATTACTTATTTAAAGTGATCACTGGTAAAGAAGGTATGGGCTACG
GCGACTTTAAATTGCTTGCAGCATTAGGAGCATGGATGGGGCCATTGATGCTGCCGTTAATTGTGTTATTGTCATCGTTA
CTTGGCGCAATCATTGGCATCATTTTATTAAAATTAAGAAATGACAATCAGCCTTTTGCTTTTGGGCCATATATTGCCAT
TGCTGGTTGGGTTGCCTTTTTATGGGGTGATCAGATTATGAAAATTTATTTGGGAGGTTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (138-247)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (22-128)

3D structure

• AlphaFold DB: A0A1E3M8A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Acinetobacter baumannii D1279779	98.601	100	0.986
pilD	Acinetobacter nosocomialis M2	98.252	100	0.983
pilD	Vibrio cholerae strain A1552	53.875	94.755	0.51
pilD	Vibrio campbellii strain DS40M4	51.971	97.552	0.507
pilD	Neisseria gonorrhoeae MS11	47.348	92.308	0.437