Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GQF94_RS05490 Genome accession   NZ_CP047002
Coordinates   1119697..1120353 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain J-8     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1114697..1125353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQF94_RS05460 (GQF94_05440) - 1115827..1116567 (+) 741 Protein_1086 hypothetical protein -
  GQF94_RS05480 (GQF94_05460) pgsA 1117263..1117811 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GQF94_RS05485 (GQF94_05465) uvrC 1117868..1119700 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GQF94_RS05490 (GQF94_05470) letA 1119697..1120353 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GQF94_RS25690 - 1120495..1120566 (+) 72 Protein_1090 transcriptional regulator -
  GQF94_RS05495 (GQF94_05475) yecU 1120649..1120825 (+) 177 WP_000590347.1 protein YecU -
  GQF94_RS05500 (GQF94_05480) yecF 1120812..1121036 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  GQF94_RS05505 (GQF94_05485) sdiA 1121103..1121825 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  GQF94_RS05510 (GQF94_05490) tcyN 1122055..1122807 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GQF94_RS05515 (GQF94_05495) tcyL 1122804..1123472 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  GQF94_RS05520 (GQF94_05500) dcyD 1123487..1124473 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=356754 GQF94_RS05490 WP_000611335.1 1119697..1120353(-) (letA) [Escherichia coli strain J-8]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=356754 GQF94_RS05490 WP_000611335.1 1119697..1120353(-) (letA) [Escherichia coli strain J-8]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486