Detailed information NTG0035606

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BAMTA208_RS19590
• Genome accession: NC_017188
• Coordinates: 3871546..3872742 (-)
• Length: 398 a.a.
• NCBI ID: WP_013354214.1
• Uniprot ID: A0A9P1NK46
• Organism: Bacillus amyloliquefaciens TA208
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3866546..3877742

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BAMTA208_RS21105 (BAMTA208_20305)	-	3867508..3867771 (-)	264	WP_013354210.1	hypothetical protein	-
BAMTA208_RS19575 (BAMTA208_20310)	-	3867950..3869368 (-)	1419	WP_014471292.1	sensor histidine kinase	-
BAMTA208_RS19580 (BAMTA208_20315)	-	3869365..3870048 (-)	684	WP_013354212.1	response regulator transcription factor	-
BAMTA208_RS19585 (BAMTA208_20320)	-	3870262..3871173 (+)	912	WP_013354213.1	PepSY domain-containing protein	-
BAMTA208_RS19590 (BAMTA208_20325)	htrA	3871546..3872742 (-)	1197	WP_013354214.1	S1C family serine protease	Regulator
BAMTA208_RS19595 (BAMTA208_20330)	vicX	3872829..3873623 (-)	795	WP_013354215.1	MBL fold metallo-hydrolase	Regulator
BAMTA208_RS19600 (BAMTA208_20335)	-	3873639..3874478 (-)	840	WP_014471293.1	two-component system regulatory protein YycI	-
BAMTA208_RS19605 (BAMTA208_20340)	yycH	3874465..3875823 (-)	1359	WP_014471294.1	two-component system activity regulator YycH	-
BAMTA208_RS19610 (BAMTA208_20345)	walK	3875813..3877648 (-)	1836	WP_014471295.1	cell wall metabolism sensor histidine kinase WalK	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42734.68 Da
• Isoelectric Point: 7.4579

>NTDB_id=35606 BAMTA208_RS19590 WP_013354214.1 3871546..3872742(-) (htrA) [Bacillus amyloliquefaciens TA208]
MDYNRDDEQYAPEQPRRSKRGYFLSSLIGVIVGAALMGLLLPYWTGGDHGESSKSANQRIGSEQVKTVNVNINDAVTNMV
SRVSDSVVGVLNIQKTDIWGEGGEAGSGSGVIYKKNGNTSYIVTNHHVIEGATEIEISLKDDSRVPAELIGSDRLMDLAV
LKVKTDKIKSVAQFGNSDQVKVGEPVIAIGNPLGLEFAGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDAAINPGN
SGGALMDISGKVVGINSMKIAESAVEGIGLSIPSKLVIPVIQDLEKYGEVRRPFLGIEMKSLTDIASYHWSQTLKLPKGV
KTGAVIMGVDAFSPAGKAGLKKLDVITGFDGHKVNDIVDLRERLYRKKIGDRVKITFYRSGKKKTAEVKLTEADRLQK

Nucleotide

• Length: 1197 bp

>NTDB_id=35606 BAMTA208_RS19590 WP_013354214.1 3871546..3872742(-) (htrA) [Bacillus amyloliquefaciens TA208]
GTGGATTATAATCGCGATGATGAACAGTACGCCCCCGAGCAGCCCCGCCGCAGCAAGAGAGGATACTTCCTTTCAAGTCT
GATCGGTGTCATCGTCGGGGCCGCGCTCATGGGTTTACTGCTGCCGTACTGGACAGGCGGAGACCATGGAGAAAGCAGCA
AAAGCGCCAATCAGCGCATCGGCAGCGAACAGGTGAAAACAGTCAACGTAAATATCAATGATGCTGTCACGAATATGGTC
AGCCGTGTATCGGATTCGGTAGTCGGCGTTCTCAATATCCAAAAGACCGATATTTGGGGAGAGGGCGGCGAAGCGGGAAG
CGGGTCCGGCGTCATTTACAAAAAGAACGGAAACACTTCTTATATCGTAACCAATCACCATGTCATTGAAGGTGCGACTG
AAATTGAGATCAGCCTGAAAGATGACTCGCGCGTGCCTGCCGAGCTGATCGGGAGCGACCGTCTGATGGATCTTGCCGTG
TTGAAGGTGAAGACTGATAAAATCAAATCGGTCGCCCAATTCGGCAATTCTGATCAAGTGAAAGTTGGCGAGCCGGTCAT
TGCGATCGGAAACCCGCTCGGACTTGAATTTGCGGGATCGGTGACACAAGGGATCATTTCAGGAACGGAAAGGGCGGTTC
CCGTTGACTCAAACGGCGACGGACAGCCTGATTGGAATGCGGAAGTGCTGCAGACCGACGCCGCGATTAATCCCGGCAAC
AGCGGCGGCGCTTTGATGGATATATCGGGCAAGGTGGTCGGCATCAACTCAATGAAGATTGCTGAATCCGCCGTTGAAGG
AATCGGCCTGTCCATCCCGTCAAAGCTTGTCATTCCCGTTATTCAGGATTTAGAAAAATACGGAGAAGTCAGACGGCCTT
TCCTCGGTATTGAGATGAAATCTTTAACGGATATTGCGAGCTACCATTGGAGCCAGACGCTCAAACTTCCGAAGGGTGTT
AAAACCGGAGCGGTCATTATGGGTGTCGACGCGTTTTCACCGGCTGGAAAAGCAGGCTTGAAAAAGCTCGACGTGATCAC
CGGATTCGACGGACATAAGGTCAATGACATTGTCGATCTCCGTGAGCGTCTGTATCGCAAAAAGATCGGCGACCGTGTCA
AGATCACGTTCTACCGTTCAGGAAAGAAAAAAACAGCGGAAGTCAAACTGACAGAAGCGGATCGATTGCAGAAATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-255)

• PDZ domain (PDZ_2) (293-390)

• Peptidase family M50 (Peptidase_M50) (320-394)

3D structure

• AlphaFold DB: A0A9P1NK46

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.687	99.497	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.602	97.236	0.405
htrA	Streptococcus mitis NCTC 12261	40.26	96.734	0.389