Detailed information NTG0035606

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAAV_RS10035
• Genome accession: NC_013450
• Coordinates: 1983410..1984453 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus subsp. aureus ED98
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1978410..1989453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAAV_RS10005 (SAAV_1944)	-	1978831..1980087 (-)	1257	WP_001795108.1	aminopeptidase	-
SAAV_RS10010 (SAAV_1945)	-	1980090..1980290 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAAV_RS10015 (SAAV_1946)	-	1980437..1980901 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAAV_RS10020 (SAAV_1947)	-	1980908..1981183 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAAV_RS10025 (SAAV_1948)	-	1981461..1982678 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SAAV_RS10030 (SAAV_1949)	vraR	1982791..1983420 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SAAV_RS10035 (SAAV_1950)	vraS	1983410..1984453 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAAV_RS10040 (SAAV_1951)	liaF	1984450..1985151 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAAV_RS10045 (SAAV_1952)	-	1985166..1985552 (-)	387	WP_001110179.1	hypothetical protein	-
SAAV_RS10050 (SAAV_1953)	map	1985769..1986527 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAAV_RS10060 (SAAV_1954)	-	1987058..1988044 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
SAAV_RS10065 (SAAV_1955)	-	1988475..1988888 (-)	414	WP_001557448.1	hypothetical protein	-
SAAV_RS10070	-	1988917..1989027 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=35606 SAAV_RS10035 WP_001017131.1 1983410..1984453(-) (vraS) [Staphylococcus aureus subsp. aureus ED98]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=35606 SAAV_RS10035 WP_001017131.1 1983410..1984453(-) (vraS) [Staphylococcus aureus subsp. aureus ED98]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1