Detailed information NTG0354068

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GPA00_RS02615
• Genome accession: NZ_CP046629
• Coordinates: 532003..534573 (-)
• Length: 856 a.a.
• NCBI ID: WP_074450865.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 527003..539573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS02595 (GPA00_02595)	-	527440..528552 (-)	1113	WP_232524226.1	MFS transporter	-
GPA00_RS02600 (GPA00_02600)	-	528765..529322 (-)	558	WP_198362632.1	DNA-3-methyladenine glycosylase I	-
GPA00_RS02605 (GPA00_02605)	ruvA	529352..529945 (-)	594	WP_024344431.1	Holliday junction branch migration protein RuvA	Machinery gene
GPA00_RS02610 (GPA00_02610)	hexB	529946..531889 (-)	1944	WP_157327446.1	DNA mismatch repair endonuclease MutL	Machinery gene
GPA00_RS02615 (GPA00_02615)	hexA	532003..534573 (-)	2571	WP_074450865.1	DNA mismatch repair protein MutS	Machinery gene
GPA00_RS02620 (GPA00_02620)	-	534560..534913 (-)	354	WP_027968295.1	YlbF family regulator	-
GPA00_RS02625 (GPA00_02625)	argR	534910..535347 (-)	438	WP_021143308.1	arginine repressor	-
GPA00_RS02630 (GPA00_02630)	argS	535537..537228 (+)	1692	WP_157327448.1	arginine--tRNA ligase	-
GPA00_RS02635 (GPA00_02635)	-	537374..538798 (-)	1425	Protein_523	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96002.26 Da
• Isoelectric Point: 4.8397

>NTDB_id=354068 GPA00_RS02615 WP_074450865.1 532003..534573(-) (hexA) [Streptococcus equinus strain CNU G6]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTAVDSTKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFYATSLSDFAS
LKSEILNLKAREIVVGYELSEEEKHSLVKQLNLLLSFEQERFEDVHLIDSNLASLEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNREQIEERQNIIQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFESPYLDKLVNSIDTLPELESLISSAIDP
DAQAVITEGSIIKTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TALSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRADSILTNLESGAAQLHLTPEVDSE
PVATESEVSEPVVEQLSLFAEDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=354068 GPA00_RS02615 WP_074450865.1 532003..534573(-) (hexA) [Streptococcus equinus strain CNU G6]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTTAAAAAAGACTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGATTTTTACGAATTATTTTACGATGATGCAGTTAAGGCTGCACAGATTTTAGAGATTAGTTTGACTAGTC
GAAATAAAAACGCTGAAAATCCTATTCCAATGGCAGGGGTACCATATCACTCAGCTCAGCAATATATTGATGTCCTTGTT
GAAATGGGCTACAAAGTTGCGATTGCAGAACAAATGGAAGATCCCAAGAAAGCAGTCGGTGTTGTAAAACGTGAAGTTGT
TCAAGTCATTACGCCAGGTACGGCAGTTGATTCGACAAAACCTGACAATGCCAATAATTTCTTGGTGGCTATTGATTCTG
ATGGCAAGACTTTTGGTCTAGCTTACATGGATGTGTCGACAGGTGAGTTTTATGCGACAAGTCTGTCAGATTTTGCCAGT
CTTAAAAGTGAAATCCTAAACCTTAAAGCACGTGAGATTGTTGTTGGCTACGAACTTTCAGAAGAAGAAAAACACAGTCT
TGTTAAACAACTCAATTTGCTTTTATCGTTTGAACAAGAGCGTTTTGAAGATGTGCACTTGATTGATTCTAATTTGGCAT
CTTTGGAGATTTCAGCTGCTGAGAAATTACTACAGTACGTCCATACCACTCAAAAACGTGAGCTCAGCCATTTGCAAAAA
TTGGTTCACTATGAAATCAAAGATTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTGTTAGAAAATGCACG
TACAAGCAAGAAACACGGTAGTCTTTATTGGTTGCTTGATGAGACAAAGACAGCTATGGGGATGCGTCTTTTGCGTAATT
GGATCGACCGTCCTTTGGTTAATCGAGAACAAATCGAAGAACGTCAAAATATCATTCAAGTTTTCTTAGACAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTTAAGGGTGTTTATGATATTGAACGCTTGGCGAGTCGTGTGTCATTTGGTAAGGC
TAATCCAAAAGACCTTCTTCAACTTGGTCATACTTTGGGGCAAGTACCTACTATCAAGGCTATTTTGGAATCCTTTGAAA
GTCCATACCTTGACAAACTTGTCAACAGCATTGACACTCTTCCTGAGTTGGAATCATTGATTAGCTCTGCTATTGACCCA
GATGCTCAAGCTGTCATCACAGAAGGTAGCATCATTAAAACTGGTTTTGATGAGACTTTGGATAAATACCGCAAAGTCAT
GCGTGAAGGTACAAGCTGGATTGCTGAGATTGAAGCCAAAGAACGTGCCGCAAGTGGTATTACAAATCTAAAAATTGATT
ACAATAAAAAAGATGGCTATTATTTCCATGTCACAAATTCTAACCTTTCTTTGGTGCCAGATTATTTCTTCCGTAAAGCA
ACTTTGAAGAACTCAGAACGTTTTGGTACAGCAGAATTGGCTAAAATTGAAGGTGAAATGCTGGAAGCGCGTGAACAATC
AGCAAGCCTAGAATACGATATTTTCATGCGTGTTCGTGCGCAGGTTGAACGTTATATTTCTCGTTTGCAAGACTTAGCAA
AAGCTATTTCAACTGTCGATGTCTTACAAAGTTTAGCTGTGGTCGCGGAAAATAATCATTATGTGCGTCCAACTTTCAAC
GATAGCCATGAGATTAAGATTGAAAAAGGTCGCCATGCCGTTGTCGAAAAAGTCATGGGCACTCAAGAATATATTCCAAA
TACGATTACATTTGGTAGAAATACTAATATTCAGCTGATTACTGGTCCTAATATGAGTGGTAAGTCAACGTATATGCGTC
AGCTAGCATTGACTGTTATCATGGCACAAATGGGGTCTTATGTCGCTGCTGAAAGTGTCAGCCTACCAGTCTTCGATGCT
ATTTTCACACGTATTGGTGCAGCAGATGACTTGATTTCAGGTCAGTCAACCTTCATGGTAGAAATGATGGAAGCTAACCA
AGCTATTAAACGTGCTAGTGATAAGTCTTTGATTCTCTTTGATGAATTGGGACGTGGTACGGCTACCTATGATGGTATGG
CTTTGGCACAATCTATTATTGAGTATATTCATGACCATATTGGGGCTAAAACGATGTTTGCAACACACTATCATGAATTG
ACAGCTCTGTCAACGACGTTGACACACCTTGTCAACGTCCATGTTGCAACCCTTGAACGTAATGGTGATGTGACTTTCCT
TCACAAGATTGCAGAAGGACCAGCTGATAAATCCTATGGTATTCACGTTGCGAAAATTGCAGGTCTACCAGAAGACTTAT
TGCAGCGTGCAGACAGCATTTTAACCAACCTTGAATCAGGTGCTGCGCAGCTTCATTTGACACCAGAAGTTGACAGTGAA
CCAGTAGCAACTGAGTCAGAAGTTTCAGAACCTGTAGTGGAGCAATTAAGTCTTTTTGCAGAAGATTCTTCTAATCAAGA
AGTGATTGAAGCACTTAAGAAAGTTGATTTGATGAACTTGACACCTATGCAGGCTATGAATGTCATCTATGAATTGAAAA
ATATGTTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.196	100	0.722
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382