Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GPA00_RS02610 Genome accession   NZ_CP046629
Coordinates   529946..531889 (-) Length   647 a.a.
NCBI ID   WP_157327446.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 524946..536889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS02590 (GPA00_02590) cinA 526067..527326 (-) 1260 WP_157327439.1 competence/damage-inducible protein A Machinery gene
  GPA00_RS02595 (GPA00_02595) - 527440..528552 (-) 1113 WP_232524226.1 MFS transporter -
  GPA00_RS02600 (GPA00_02600) - 528765..529322 (-) 558 WP_198362632.1 DNA-3-methyladenine glycosylase I -
  GPA00_RS02605 (GPA00_02605) ruvA 529352..529945 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA Machinery gene
  GPA00_RS02610 (GPA00_02610) hexB 529946..531889 (-) 1944 WP_157327446.1 DNA mismatch repair endonuclease MutL Machinery gene
  GPA00_RS02615 (GPA00_02615) hexA 532003..534573 (-) 2571 WP_074450865.1 DNA mismatch repair protein MutS Machinery gene
  GPA00_RS02620 (GPA00_02620) - 534560..534913 (-) 354 WP_027968295.1 YlbF family regulator -
  GPA00_RS02625 (GPA00_02625) argR 534910..535347 (-) 438 WP_021143308.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72850.94 Da        Isoelectric Point: 5.2853

>NTDB_id=354067 GPA00_RS02610 WP_157327446.1 529946..531889(-) (hexB) [Streptococcus equinus strain CNU G6]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGVAQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLIAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMTLISS
AIAESLRAQDLIPDALENLAKSSTRGLPKPEQTSLPLKQSNLYYDKERHDFFVKSDTVEEQPVQLFNEVDTAVKEVDKQS
SVKYAQRSTQGNLADGEHDDLDFKNKSKINKLLENLDGEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYRDKIGDVDASLQQLLMPYLFEFSGADFIKLQEKMELLNQVGINLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=354067 GPA00_RS02610 WP_157327446.1 529946..531889(-) (hexB) [Streptococcus equinus strain CNU G6]
ATGAGTAAAATTATCGAGTTACCAGAGGTTCTAGCCAACCAAATTGCTGCTGGTGAGGTTATTGAACGCCCGGCTAGCGT
GGTCAAGGAATTAGTAGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACTATTGAAATCGAAGAGTCTGGTTTGAAAA
AAATCCAAGTTACTGATAACGGTGAGGGAGTTGCTCAAGAGGATGTTGCTCTTAGTTTGCACCGTCACGCGACTAGTAAG
ATTAAAAGTCAAGCCGACCTGTTTCGAATCAGAACGCTTGGTTTCCGTGGCGAAGCCATTCCTTCCATCGCTTCAATCAG
TCATTTTACGGTGAAAACAGCAACGGCTGATGAAAATTATGGGACGCTTTTGATTGCTAAGGGTGGCGAAATTGAAAAAC
AAGAGCCAATCTCAACACCCGTTGGAACAAAAATTACAGTTGAAAATCTGTTTTACAACACACCAGCTCGTCTTAAGTAT
ATGAAGAGTCTACAGTCAGAGTTGGCACATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCTGAAATTGCCTT
CACTTTGATTAATGATGGACGTCAGATGACAACGACATCAGGTACTGGAGATTTGCGCCAAGCGATTGCTGGGATTTATG
GCTTAAACACAGCTAAGAAGATGATTGAGATTTCAAATGCAGATCTTGATTTTGAGGTATCAGGTTACATTAGTTTACCT
GAATTGACGCGTGCGAATCGCAATTATATTACGATTTTGATTAACGGGCGTTACATCAAAAATTTCTTACTGAATCGTGC
CATCTTGGACGGCTATGGTTCAAAATTGATGGTTGGTCGTTTCCCGATTGCTGTCATTGATATCCAGATTGACCCTTATC
TTGCTGATGTTAATGTTCATCCAACAAAGCAAGAAGTTCGTATTTCAAAAGAAAAAGAACTGATGACTCTCATCAGCTCA
GCTATTGCAGAGAGTTTACGTGCTCAGGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGCACTCGTGGCTT
GCCTAAACCAGAGCAAACGAGTCTGCCCTTAAAACAATCAAATCTTTATTATGACAAAGAGCGTCACGATTTCTTTGTGA
AATCAGATACTGTTGAAGAGCAGCCAGTTCAGCTGTTTAATGAGGTTGACACAGCTGTCAAGGAAGTTGACAAGCAGTCT
TCAGTCAAATACGCACAGCGTTCTACTCAGGGAAACCTTGCAGACGGTGAGCATGATGACCTTGATTTCAAAAATAAATC
TAAAATTAATAAGTTGCTCGAAAATCTTGATGGTGAAGAATCATCAACTTTCCCTGAACTTGATTATTTTGGTCAGATGC
ATGGGACATATCTTTTTGCGCAGGGAAATGGTGGCCTTTATATCATTGACCAACATGCGGCGCAGGAACGTGTTAAATAT
GAATATTATCGTGACAAAATTGGTGACGTCGATGCTTCACTCCAACAATTGCTCATGCCATATTTGTTTGAGTTTTCTGG
AGCAGATTTTATCAAGCTTCAAGAAAAAATGGAGCTTTTAAATCAAGTTGGCATCAATCTAGAACCATATGGGAACAATA
CATTTATTCTTCGTGAACATCCTATTTGGATGAAAGAAGAGGAAATTGAATCGGCTGTTTATGAAATGTGTGATATGTTA
CTTTTGACAAATGAAGTATCTGTCAAAAAATACCGTGCAGAGTTAGCGATTATGATGTCATGCAAACGTTCAATCAAAGC
TAATCACACTCTTGATGATTATTCAGCACGTCAACTTCTAGTGCAATTATCACAATGTAAGAATCCGTATAACTGTCCAC
ACGGTCGTCCTGTCCTGGTCAATTTTACCAAATCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.732

100

0.717