Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GPA00_RS00545 Genome accession   NZ_CP046629
Coordinates   111714..113066 (-) Length   450 a.a.
NCBI ID   WP_024343735.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 106714..118066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS00505 (GPA00_00505) - 106751..106972 (-) 222 WP_001009056.1 hypothetical protein -
  GPA00_RS00510 (GPA00_00510) mobT 107015..108220 (-) 1206 WP_000398284.1 MobT family relaxase -
  GPA00_RS00515 (GPA00_00515) - 108243..108395 (-) 153 WP_000879507.1 hypothetical protein -
  GPA00_RS00520 (GPA00_00520) - 108398..109783 (-) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  GPA00_RS00525 (GPA00_00525) - 109812..110198 (-) 387 WP_000985015.1 YdcP family protein -
  GPA00_RS00530 (GPA00_00530) - 110214..110528 (-) 315 WP_000420682.1 YdcP family protein -
  GPA00_RS00540 (GPA00_00540) vicX 110904..111713 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  GPA00_RS00545 (GPA00_00545) vicK 111714..113066 (-) 1353 WP_024343735.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPA00_RS00550 (GPA00_00550) yycF 113059..113769 (-) 711 WP_021142846.1 response regulator YycF -
  GPA00_RS00555 (GPA00_00555) - 114077..114841 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  GPA00_RS00560 (GPA00_00560) - 114846..115655 (+) 810 WP_157327105.1 transporter substrate-binding domain-containing protein -
  GPA00_RS00565 (GPA00_00565) - 115671..116375 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  GPA00_RS00570 (GPA00_00570) - 116385..117032 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  GPA00_RS00575 (GPA00_00575) - 117064..117672 (-) 609 WP_074450680.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51391.34 Da        Isoelectric Point: 4.7300

>NTDB_id=354039 GPA00_RS00545 WP_024343735.1 111714..113066(-) (vicK) [Streptococcus equinus strain CNU G6]
MNNIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYTYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=354039 GPA00_RS00545 WP_024343735.1 111714..113066(-) (vicK) [Streptococcus equinus strain CNU G6]
ATGAATAATATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTACTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATATACTGAAGATATCATTATCGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGCTTGGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTACATGACTGATGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACAGCTCAGCAGCAACTTAATCTGGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGACGATAGCGATTATACCTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGCCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTAAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTGATTGCTGTTTTACATGATACAACGGAACAGGAAAAAGAAGACCGAGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCATATTTGGAAGCTTTGGATGAAGGTGCCCTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGCATGATTCGAATGATTTCTGATTTGCTCAA
TTTGTCTCGAATTGATAATCAGACTGTTCAGCTTGAAGTTGAAATGACTAACTTTACAGCATTTATGACATCAATTTTGA
ACCGTTTTGACCAAATTAAGAGTCAACATACTGTCGCTGGTAAGCAGTACGAGATTGTCAGAGATTATCCAATCAAATCT
ATCTGGTTAGAAATTGACCCAGATAAAATGACGCAAGTTCTGGATAATATCCTTAATAATGCAATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAAGGTCTTGGTATTC
CTAAGAAAGATTTGCCACTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGTCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterProScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622