Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GO596_RS03460 Genome accession   NZ_CP046628
Coordinates   677963..679906 (+) Length   647 a.a.
NCBI ID   WP_027968297.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 672963..684906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS03445 (GO596_03445) argR 674505..674942 (+) 438 WP_021143308.1 arginine repressor -
  GO596_RS03450 (GO596_03450) - 674939..675292 (+) 354 WP_157339200.1 YlbF family regulator -
  GO596_RS03455 (GO596_03455) hexA 675279..677849 (+) 2571 WP_157339201.1 DNA mismatch repair protein MutS Machinery gene
  GO596_RS03460 (GO596_03460) hexB 677963..679906 (+) 1944 WP_027968297.1 DNA mismatch repair endonuclease MutL Machinery gene
  GO596_RS03465 (GO596_03465) ruvA 679907..680500 (+) 594 WP_024344431.1 Holliday junction branch migration protein RuvA Machinery gene
  GO596_RS03470 (GO596_03470) - 680530..681087 (+) 558 WP_162496024.1 DNA-3-methyladenine glycosylase I -
  GO596_RS03475 (GO596_03475) - 681210..682412 (+) 1203 WP_157339202.1 MFS transporter -
  GO596_RS03480 (GO596_03480) cinA 682526..683785 (+) 1260 WP_157339203.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72891.01 Da        Isoelectric Point: 5.2853

>NTDB_id=353975 GO596_RS03460 WP_027968297.1 677963..679906(+) (hexB) [Streptococcus equinus strain CNU 77-23]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGIAQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLIAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMTLISS
AIAESLRAQDLIPDALENLAKSSTRGLPKPEQTSLPLKQSNLYYDKERHDFFVKSDTVEEQPVQLFNEVDTPVKEVDKQS
SVKYAQRSTQGNLADGEHDDLDFKNKSKINKLLENLDGEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYRDKIGDVDASLQQLLMPYLFEFSGADFIKLQEKMELLNQVGINLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=353975 GO596_RS03460 WP_027968297.1 677963..679906(+) (hexB) [Streptococcus equinus strain CNU 77-23]
ATGAGTAAAATTATCGAGTTACCAGAGGTTCTAGCCAACCAAATTGCTGCTGGTGAGGTTATTGAACGCCCGGCTAGCGT
GGTCAAGGAATTAGTAGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACTATTGAAATCGAAGAGTCTGGTTTGAAAA
AAATCCAAGTTACTGATAACGGTGAGGGAATTGCTCAAGAGGATGTTGCTCTTAGTTTGCACCGTCACGCGACTAGTAAG
ATTAAAAGTCAAGCCGACCTGTTTCGAATCAGAACGCTTGGTTTCCGTGGCGAAGCCATTCCTTCCATCGCTTCAATCAG
TCATTTTACGGTGAAAACAGCAACGGCTGATGAAAATTATGGGACGCTTTTGATTGCTAAGGGTGGCGAAATTGAAAAAC
AAGAGCCAATCTCAACGCCCGTTGGAACAAAAATTACAGTTGAAAATCTGTTTTACAACACACCAGCTCGTCTTAAGTAT
ATGAAGAGTCTACAGTCAGAGTTGGCACATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCTGAAATTGCCTT
CACTTTGATTAATGATGGACGTCAGATGACAACGACATCAGGTACTGGAGATTTGCGCCAAGCGATTGCTGGGATTTATG
GCTTAAACACAGCTAAGAAGATGATTGAGATTTCAAATGCAGATCTTGATTTTGAGGTATCAGGTTACATTAGTTTACCT
GAATTGACGCGTGCGAATCGCAATTATATTACGATTTTGATTAACGGACGTTACATCAAAAATTTCTTACTGAATCGTGC
CATCTTGGACGGTTATGGTTCAAAATTGATGGTTGGTCGTTTCCCGATTGCTGTCATTGATATCCAGATTGACCCTTATC
TTGCTGATGTCAATGTTCATCCAACAAAGCAAGAAGTTCGTATCTCAAAGGAAAAAGAATTGATGACTCTCATCAGCTCA
GCTATTGCAGAGAGTTTACGTGCTCAGGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGCACTCGTGGCTT
GCCTAAACCAGAGCAAACGAGTCTGCCCTTAAAACAATCAAATCTTTATTATGACAAAGAGCGTCACGATTTCTTTGTGA
AATCAGATACTGTTGAAGAGCAGCCAGTTCAGCTGTTTAATGAGGTTGACACACCTGTCAAGGAAGTTGACAAGCAGTCT
TCAGTCAAATACGCACAGCGTTCTACTCAGGGAAACCTTGCAGACGGCGAGCATGATGACCTTGATTTCAAAAATAAATC
TAAAATTAATAAGTTGCTCGAAAATCTTGATGGTGAAGAATCATCAACTTTCCCTGAACTTGATTATTTTGGTCAGATGC
ATGGGACATATCTTTTTGCGCAGGGAAATGGTGGCCTTTATATCATTGACCAACATGCGGCGCAGGAACGTGTTAAATAT
GAATATTATCGTGACAAAATTGGTGACGTCGATGCTTCACTCCAACAATTGCTCATGCCATATTTGTTTGAGTTTTCTGG
AGCAGATTTTATCAAGCTTCAAGAAAAAATGGAGCTTTTAAATCAAGTTGGCATCAATCTAGAACCATATGGGAACAATA
CATTTATTCTTCGTGAACATCCTATTTGGATGAAAGAAGAGGAGATTGAATCGGCTGTTTATGAAATGTGTGATATGTTG
CTTTTGACGAATGAAGTATCTGTCAAAAAATACCGTGCAGAGTTAGCGATTATGATGTCATGTAAACGTTCAATTAAAGC
TAATCACACTCTTGATGATTATTCAGCACGTCAACTTCTAGTGCAATTATCACAATGTAAGAATCCGTATAACTGTCCAC
ACGGTCGTCCTGTTCTGGTCAACTTTACCAAATCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.884

100

0.719