Detailed information NTG0353974

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GO596_RS03455
• Genome accession: NZ_CP046628
• Coordinates: 675279..677849 (+)
• Length: 856 a.a.
• NCBI ID: WP_157339201.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 670279..682849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS03435 (GO596_03435)	-	671055..672479 (+)	1425	Protein_600	PTS transporter subunit EIIC	-
GO596_RS03440 (GO596_03440)	argS	672624..674315 (-)	1692	WP_074533438.1	arginine--tRNA ligase	-
GO596_RS03445 (GO596_03445)	argR	674505..674942 (+)	438	WP_021143308.1	arginine repressor	-
GO596_RS03450 (GO596_03450)	-	674939..675292 (+)	354	WP_157339200.1	YlbF family regulator	-
GO596_RS03455 (GO596_03455)	hexA	675279..677849 (+)	2571	WP_157339201.1	DNA mismatch repair protein MutS	Machinery gene
GO596_RS03460 (GO596_03460)	hexB	677963..679906 (+)	1944	WP_027968297.1	DNA mismatch repair endonuclease MutL	Machinery gene
GO596_RS03465 (GO596_03465)	ruvA	679907..680500 (+)	594	WP_024344431.1	Holliday junction branch migration protein RuvA	Machinery gene
GO596_RS03470 (GO596_03470)	-	680530..681087 (+)	558	WP_162496024.1	DNA-3-methyladenine glycosylase I	-
GO596_RS03475 (GO596_03475)	-	681210..682412 (+)	1203	WP_157339202.1	MFS transporter	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96016.33 Da
• Isoelectric Point: 4.8701

>NTDB_id=353974 GO596_RS03455 WP_157339201.1 675279..677849(+) (hexA) [Streptococcus equinus strain CNU 77-23]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTAVDSTKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFYATSLSDFAS
LKSEILNLKAREIVVGYELSEEEKHSLVKQLNLLLSFEQERFEDVHLIDSNLASLEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNREQIEERQNIIQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFESPYLDKLVNSIDTLPELESLISSAIDP
DAQAVITEGSIIKTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TALSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRADSILTKLESGAAQLHLTPEVDSE
PVATESEVSEPVVEQLSLFAEDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=353974 GO596_RS03455 WP_157339201.1 675279..677849(+) (hexA) [Streptococcus equinus strain CNU 77-23]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTTAAAAAAGACTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGATTTTTACGAATTATTTTACGATGATGCAGTTAAGGCTGCACAGATTTTAGAGATTAGTTTGACTAGTC
GAAATAAAAATGCTGAAAATCCTATTCCAATGGCAGGGGTACCATATCACTCAGCTCAGCAATATATTGATGTCCTTGTT
GAAATGGGCTACAAAGTTGCGATTGCAGAACAAATGGAAGATCCCAAGAAAGCAGTCGGTGTTGTAAAACGTGAAGTTGT
TCAAGTCATTACGCCAGGTACGGCAGTTGATTCGACAAAACCTGACAATGCCAATAATTTCTTGGTGGCTATTGATTCTG
ATGGCAAGACTTTTGGTCTAGCTTACATGGATGTGTCGACAGGTGAGTTTTATGCGACAAGTCTGTCAGATTTTGCCAGT
CTTAAAAGTGAAATCCTAAACCTTAAAGCACGTGAGATTGTTGTTGGCTACGAACTTTCAGAAGAAGAAAAACACAGTCT
TGTTAAACAACTCAATTTGCTTTTATCGTTTGAACAAGAGCGTTTTGAAGATGTGCACTTGATTGATTCTAATTTGGCAT
CTTTGGAGATTTCAGCTGCTGAGAAATTACTACAGTACGTCCATACCACTCAAAAACGTGAGCTCAGCCATTTGCAAAAA
TTGGTTCACTATGAAATCAAAGATTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTGTTAGAAAATGCACG
TACAAGCAAGAAACACGGTAGTCTTTATTGGTTGCTTGATGAGACAAAGACAGCTATGGGGATGCGTCTTTTGCGTAATT
GGATCGACCGTCCTTTGGTTAATCGAGAACAAATCGAAGAACGTCAAAATATCATTCAAGTTTTCTTAGACAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTTAAGGGTGTTTATGATATTGAACGCTTGGCGAGTCGTGTGTCATTTGGTAAGGC
TAATCCAAAAGACCTTCTTCAACTTGGTCATACTTTGGGGCAAGTACCTACTATCAAGGCTATTTTGGAATCCTTTGAAA
GTCCATACCTTGACAAACTTGTCAACAGCATTGACACTCTTCCTGAGTTGGAATCATTGATTAGCTCTGCTATTGACCCA
GATGCTCAAGCTGTCATCACAGAAGGTAGCATCATTAAAACTGGTTTTGATGAGACTTTGGATAAATACCGCAAAGTCAT
GCGTGAAGGTACAAGCTGGATTGCTGAGATTGAAGCCAAAGAACGTGCCGCAAGTGGTATTACAAATCTAAAAATTGATT
ACAATAAAAAAGATGGCTATTATTTCCATGTCACAAATTCTAACCTTTCTTTGGTGCCAGATTATTTCTTCCGTAAAGCA
ACTTTGAAGAACTCAGAACGTTTTGGTACAGCAGAATTGGCTAAAATTGAAGGTGAAATGCTGGAAGCGCGTGAACAATC
AGCAAGCCTAGAATACGATATTTTCATGCGTGTTCGTGCGCAGGTGGAGCGCTATATTTCACGTTTGCAAGACTTAGCAA
AAGCTATTTCAACGGTCGATGTCTTACAAAGTTTAGCTGTGGTCGCTGAAAATAATCATTATGTGCGTCCAACTTTCAAC
GATAGCCATGAGATTAAGATTGAAAAAGGTCGTCACGCAGTCGTTGAAAAAGTCATGGGCACTCAAGAATATATTCCAAA
TACGATTACATTTGGTAGAAATACTAATATTCAGCTGATTACTGGTCCTAATATGAGTGGTAAGTCAACTTATATGCGTC
AGCTAGCATTGACTGTTATCATGGCACAAATGGGGTCTTATGTCGCTGCTGAAAGTGTCAGTCTACCAGTCTTCGATGCT
ATTTTCACACGTATTGGTGCAGCTGATGACTTGATTTCAGGTCAGTCAACCTTCATGGTAGAAATGATGGAAGCTAACCA
AGCTATTAAACGTGCTAGTGATAAGTCTTTGATTCTCTTTGATGAATTGGGACGTGGTACGGCAACCTATGATGGTATGG
CTTTGGCACAATCTATTATTGAGTATATTCATGACCATATTGGGGCTAAAACGATGTTTGCAACGCACTATCATGAATTG
ACAGCTCTGTCAACGACCTTGACACACCTTGTCAACGTCCATGTTGCAACCCTTGAACGTAATGGTGATGTGACTTTTCT
TCACAAGATTGCAGAAGGACCCGCAGATAAATCCTATGGTATTCACGTTGCGAAAATTGCAGGCTTACCAGAAGATTTAT
TACAACGTGCAGACAGCATTTTAACCAAACTTGAATCAGGTGCTGCGCAGCTTCATTTGACACCAGAAGTTGACAGTGAA
CCAGTAGCAACTGAATCAGAAGTTTCAGAACCTGTAGTGGAGCAATTAAGTCTTTTTGCAGAAGATTCTTCTAATCAAGA
AGTGATTGAAGCACTTAAGAAAGTTGATTTGATGAACTTGACACCTATGCAGGCTATGAATGTCATCTATGAATTGAAAA
ATATGTTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.196	100	0.722
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382