Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GO602_RS04365 Genome accession   NZ_CP046602
Coordinates   913203..913874 (+) Length   223 a.a.
NCBI ID   WP_003085524.1    Uniprot ID   A0A0H2Z6L5
Organism   Pseudomonas aeruginosa strain CMC-115     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 908203..918874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO602_RS04345 (GO602_04345) - 908649..910166 (-) 1518 WP_023116055.1 tripartite tricarboxylate transporter permease -
  GO602_RS04350 (GO602_04350) - 910177..910647 (-) 471 WP_003101933.1 tripartite tricarboxylate transporter TctB family protein -
  GO602_RS04355 (GO602_04355) - 910696..911679 (-) 984 WP_003085519.1 tripartite tricarboxylate transporter substrate binding protein -
  GO602_RS04360 (GO602_04360) - 911709..912992 (-) 1284 WP_058140904.1 OprD family porin -
  GO602_RS04365 (GO602_04365) ciaR 913203..913874 (+) 672 WP_003085524.1 response regulator Regulator
  GO602_RS04370 (GO602_04370) - 913867..915249 (+) 1383 WP_024916393.1 sensor histidine kinase -
  GO602_RS04375 (GO602_04375) - 915257..916093 (-) 837 WP_003085528.1 HDOD domain-containing protein -
  GO602_RS04380 (GO602_04380) - 916194..917138 (-) 945 WP_024916392.1 YgfZ/GcvT domain-containing protein -
  GO602_RS04385 (GO602_04385) - 917411..917665 (+) 255 WP_024916391.1 succinate dehydrogenase assembly factor 2 -
  GO602_RS04390 (GO602_04390) - 917649..918101 (+) 453 WP_024916390.1 protein YgfX -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24431.24 Da        Isoelectric Point: 5.1881

>NTDB_id=353840 GO602_RS04365 WP_003085524.1 913203..913874(+) (ciaR) [Pseudomonas aeruginosa strain CMC-115]
MRILLVEDHPQLAESVVQALKGAGWTVDLLQDGVAADLALASEEYALAILDVGLPRMDGFEVLARLRGRGKTLPVLMLTA
RGEVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVLGGEQLQRCGALVYDLGTRRFSLDEQPLTLTSREQAVLEA
MIARPGRVMSKEQLAAQVFGLDEEASADAIEIYVHRLRKKLEGGAVRIVTFRGLGYLLEAQGD

Nucleotide


Download         Length: 672 bp        

>NTDB_id=353840 GO602_RS04365 WP_003085524.1 913203..913874(+) (ciaR) [Pseudomonas aeruginosa strain CMC-115]
ATGCGCATCCTTCTGGTGGAAGATCATCCGCAGCTCGCCGAAAGCGTGGTCCAGGCGCTCAAGGGCGCCGGCTGGACGGT
AGACCTGCTACAGGACGGGGTGGCCGCCGACCTGGCCCTGGCCAGCGAGGAGTACGCCCTGGCGATCCTCGACGTCGGCC
TGCCGCGGATGGACGGCTTCGAGGTACTGGCGCGCCTGCGCGGGCGCGGCAAGACCCTGCCGGTGCTGATGCTGACTGCG
CGCGGCGAGGTGAAGGACCGGGTGCACGGCCTCAACCTCGGCGCCGACGACTACCTGGCCAAGCCTTTCGAACTGTCCGA
GCTGGAGGCGCGGGTCAAGGCCCTGCTGCGCCGCAGCGTGCTCGGCGGCGAACAGTTGCAGCGCTGCGGCGCGCTGGTCT
ACGACCTCGGCACCCGGCGCTTCAGCCTCGACGAGCAGCCGCTGACCCTGACCTCGCGGGAACAGGCGGTGCTGGAAGCG
ATGATCGCCCGTCCGGGGCGGGTGATGAGCAAGGAGCAACTGGCCGCCCAGGTCTTCGGCCTGGACGAGGAGGCCAGCGC
CGACGCCATCGAGATCTACGTCCACCGCCTGCGCAAGAAGCTGGAAGGCGGCGCCGTGCGCATCGTCACCTTCCGCGGCC
TCGGCTACCTGCTGGAGGCGCAGGGTGACTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-218)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z6L5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.668

100

0.377
  ciaR Streptococcus pneumoniae D39

37.668

100

0.377
  ciaR Streptococcus pneumoniae R6

37.668

100

0.377
  ciaR Streptococcus pneumoniae TIGR4

37.668

100

0.377
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.668

100

0.377

Multiple sequence alignment