Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   GOE21_RS19535 Genome accession   NZ_CP046539
Coordinates   4007224..4007856 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain FHI_NMBU_10     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4002224..4012856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOE21_RS19510 (GOE21_19510) yhfG 4002356..4002523 (+) 168 WP_000736860.1 YhfG family protein -
  GOE21_RS19515 (GOE21_19515) fic 4002513..4003115 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  GOE21_RS19520 (GOE21_19520) pabA 4003147..4003710 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  GOE21_RS19525 (GOE21_19525) argD 4003796..4005016 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  GOE21_RS19530 (GOE21_19530) yhfK 4005083..4007173 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  GOE21_RS19535 (GOE21_19535) crp 4007224..4007856 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  GOE21_RS19540 (GOE21_19540) yhfA 4008158..4008562 (+) 405 WP_001148908.1 OsmC family protein -
  GOE21_RS19545 (GOE21_19545) prkB 4008617..4009486 (-) 870 WP_001274680.1 phosphoribulokinase -
  GOE21_RS19550 (GOE21_19550) yheU 4009540..4009758 (-) 219 WP_000907085.1 YheU family protein -
  GOE21_RS19555 (GOE21_19555) yheT 4009752..4010774 (-) 1023 WP_000057405.1 hydrolase -
  GOE21_RS19560 (GOE21_19560) yheS 4010774..4012687 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=353193 GOE21_RS19535 WP_000242755.1 4007224..4007856(-) (crp) [Escherichia coli strain FHI_NMBU_10]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=353193 GOE21_RS19535 WP_000242755.1 4007224..4007856(-) (crp) [Escherichia coli strain FHI_NMBU_10]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467